Results 171 to 180 of about 93,932 (331)

Effect of Photoinitiation Process on Photo‐Crosslinking of Gelatin Methacryloyl Hydrogel Networks

open access: yesMacromolecular Rapid Communications, EarlyView.
A systematic comparison of three widely used photoinitiator systems, Eosin Y, LAP, and Ruthenium/SPS, reveals how their distinct radical‐generation mechanisms influence the stiffness, degradation, swelling, and cytocompatibility of GelMA hydrogels. This study uncovers initiator‐specific thresholds and network features critical for optimizing visible ...
Doğukan Duymaz   +2 more
wiley   +1 more source

Nephroprotective Effects of Fraxinus Hookeri Wenz. Against Renal Toxicity and DNA Oxidative Damages Induced by CCl4 in Rats

open access: yesChemistryOpen, EarlyView.
This study evaluates the nephroprotective potential of Fraxinus hookeri Wenz. (F. hookeri), a medicinal plant of the Oleaceae family, against CCl4‐induced oxidative stress. The findings demonstrate its ability to restore antioxidant defenses, renal function markers, and DNA integrity while reducing lipid peroxidation and histopathological damage.
Raheela Sarwar   +9 more
wiley   +1 more source

A Large Cohort Study to Identify Risk Factors of Acute Kidney Injury in Pediatric Patients Undergoing Intravenous Vancomycin Therapy

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT Background and Objectives The relative contribution of vancomycin exposure versus clinical factors to acute kidney injury (AKI) development in pediatric patients remains unclear. This study examined risk factors for AKI in pediatric patients receiving intravenous vancomycin therapy, with particular focus on elucidating the role of vancomycin ...
Rahul K. Goyal   +4 more
wiley   +1 more source

Interparticle Crosslinked Ion‐Responsive Microgels for 3D and 4D (Bio)Printing Applications

open access: yesSmall, EarlyView.
A novel strategy is developed that enables interparticle crosslinking of microgels, eliminating the need for filler hydrogels and preserving essential microscale void spaces to support cell migration and vascularization. These microgels possesses unique, ion‐responsive shrinking behavior primarily by the Hofmeister effect, reversible upon the removal ...
Vaibhav Pal   +8 more
wiley   +1 more source

Proteomic analysis of AQP11-null kidney: Proximal tubular type polycystic kidney disease

open access: yesBiochemistry and Biophysics Reports, 2018
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by the mutation of polycystins (PC-1 or PC-2), in which cysts start from the collecting duct to extend to all nephron segments with eventual end stage renal failure.
Tatsuya Saito   +3 more
doaj  

Targeted Delivery of miR‐34a via Anti‐CD47 Antibody Conjugates for Enhanced Cancer Immunotherapy in Triple Negative Breast Cancer

open access: yesSmall, EarlyView.
aCD47‐C‐miR34a, an antibody‐oligonucleotide platform combining an anti‐CD47 antibody with miR‐34a, is designed for targeted therapy in TNBC. This approach improved delivery and restored the tumor‐suppressing function of miR‐34a, enhanced CD8+ T‐cell activation, and inhibited tumor growth, providing a potential strategy to overcome immune evasion and ...
Youngri Ryu   +11 more
wiley   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

open access: yesSmart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan   +4 more
wiley   +1 more source

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