Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Vitamin A (retinol and retinyl esters) is present in substantial amounts in the urine of healthy adult dogs, but the mechanisms affecting its excretion are poorly understood. To assess whether the onset of urinary vitamin A excretion is dependent on dietary vitamin A intake, breed, and/or parameters of kidney function, 48 puppies from two ...
Jens Raila +2 more
wiley +1 more source
Pervasive food contaminant ochratoxin-A induces energy crisis: Mitochondrial dysfunction in human primary proximal tubule cells. [PDF]
Toxicol RepMahadeo A +6 more
europepmc +1 more source
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
Journal of Periodontal Research, EarlyView.This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Efficient kidney gene transfer and proximal tubule transduction using self-complementary AAV.cc47 vectors. [PDF]
Mol Ther Methods Clin DevPeek JL +8 more
europepmc +1 more source
Journal of Small Animal Practice, EarlyView.Objectives To investigate the discriminatory potential of serum amyloid A, neutrophil:lymphocyte ratio, monocyte:lymphocyte ratio and assess renal tubular injury in cats with pyelonephritis. Materials and Methods Diagnostic accuracy study using samples from prospectively enrolled cats and stored material.
L. R. Jessen +9 more
wiley +1 more source
Pax inhibition: stressing proximal tubule for successful repair. [PDF]
Am J Physiol Renal PhysiolKitai H, Mulcrone D, Souma T.
europepmc +1 more source
Root surface biomodification in periodontal therapy: Biological rationale and clinical applications
Periodontology 2000, EarlyView.Abstract Regenerative periodontal therapy aims to form new cementum, periodontal ligament, and alveolar bone, all sealed by gingival tissue. The root surface acts as the wound margin during this regeneration process. Root surface biomodification (root conditioning/root decontamination), therefore, seems instrumental in promoting surface decontamination
Muhammad H. A. Saleh +3 more
wiley +1 more source
Downregulation of Akt induces proximal tubule epithelial cell apoptosis via FOXO and BIM pathway in proteinuric States. [PDF]
Sci RepChhaing R, Ma Q, Schuh M, Erkan E.
europepmc +1 more source
Periodontology 2000, EarlyView.Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley +1 more source
Fasting hijacks proximal tubule circadian control mechanisms to regulate glucose reabsorption via the Nrf1/Sglt2 pathway in mice. [PDF]
Nat CommunPan X +5 more
europepmc +1 more source