Results 241 to 250 of about 53,118 (291)

Evaluation of digital radiographic measurements for the diagnosis of acute laminitis

Equine Veterinary Journal, Volume 57, Issue 4, Page 931-942, July 2025.
Abstract Background Traditional radiographic measurements of distal phalanx (Pd) displacement based on the outer hoof wall are not useful for diagnosis of acute laminitis. Objectives We hypothesised that the distance between the inner hoof wall and Pd (‘lamellar lucent zone’; LLZ) measured on lateromedial digital radiographs would be increased in ...
Georgia Skelton, Elizabeth Acutt, Darko Stefanovski, Andrew van Eps   +3 more
wiley   +1 more source

Mitophagy regulates mitochondrial number following pharmacological induction of mitochondrial biogenesis in renal proximal tubule cells. [PDF]

Front Pharmacol
Hurtado KA, Schnellmann RG.
europepmc   +1 more source

From blood flow to organ function: The physiology of autoregulatory dynamics

Experimental Physiology, EarlyView.
Niels‐Henrik Holstein‐Rathlou, Donald J. Marsh   +1 more
wiley   +1 more source

Prevalence of Proteinuria in Dogs With Immune‐Mediated Disease

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Proteinuria is associated with autoimmune diseases in humans. There is minimal evidence in the veterinary literature on proteinuria and its association with immune‐mediated disease in dogs. Hypothesis Renal proteinuria is common in dogs with immune‐mediated disease. Dogs presenting with pyrexia or immune‐mediated polyarthritis (IMPA)
James C. Barton, Alexander J. German, Erin M. O'Connell   +2 more
wiley   +1 more source

Physiology and metabolism of eukaryotic microalgae involved in aquatic photosymbioses

New Phytologist, Volume 247, Issue 1, Page 71-89, July 2025.
Summary Symbiosis between eukaryotic microalgae and heterotrophic hosts is a widespread, phylogenetically convergent, and ecologically important phenomenon in aquatic ecosystems. Partners include taxonomically diverse microalgae interacting with multicellular or unicellular hosts in marine or freshwater environments.
Daniel P. Yee, Caroline Juery, Gaëlle Toullec, Andrea Catacora‐Grundy, Charlotte Lekieffre, Daniel Wangpraseurt, Johan Decelle   +6 more
wiley   +1 more source

Carbonic anhydrase‐9‐targeted near‐infrared photoimmunotherapy as a theranostic modality for clear cell renal cell carcinoma

International Journal of Cancer, Volume 156, Issue 12, Page 2377-2388, 15 June 2025.
What's New? The cell‐surface glycoprotein carbonic anhydrase‐9 (CA9) is highly expressed in clear cell renal cell carcinoma (ccRCC), suggesting that it may be leveraged as a therapeutic target. A promising and minimally invasive approach for CA9‐targeting is near‐infrared photoimmunotherapy (NIR‐PIT).
Hiroshi Fukushima, Seiichiro Takao, Aki Furusawa, Motofumi Suzuki, Youfeng Yang, Christopher J. Ricketts, Makoto Kano, Shuhei Okuyama, Hiroshi Yamamoto, Miyu Kano, Mark W. Ball, Peter L. Choyke, W. Marston Linehan, Hisataka Kobayashi   +13 more
wiley   +1 more source

Predicting proximal tubule failed repair drivers through regularized regression analysis of single cell multiomic sequencing. [PDF]

Nat Commun
Ledru N, Wilson PC, Muto Y, Yoshimura Y, Wu H, Li D, Asthana A, Tullius SG, Waikar SS, Orlando G, Humphreys BD.   +10 more
europepmc   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, Volume 19, Issue 6, Page 1565-1581, June 2025.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

The e-liquid flavoring cinnamaldehyde induces cellular stress responses in human proximal tubule (HK-2) kidney cells. [PDF]

Biomed Pharmacother
Cox A, Brown KC, Bender C, Valentovic MA.   +3 more
europepmc   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang, Xudan Dou, Yongzhan Sun, Mengyao Wang, Jing Wang, Xinyi Cao, Haijie Xie, Linguo Xie, Weiping Tian, Jing Nie, Yupeng Chen, Chunyu Liu, Lirong Zhang   +12 more
wiley   +1 more source