Results 261 to 270 of about 53,118 (291)
Some of the next articles are maybe not open access.
1979
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
R. J. Turner, M. Silverman
openaire +3 more sources
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
R. J. Turner, M. Silverman
openaire +3 more sources
Calcium Transport by the Proximal Tubule
1986Taken together the results of these in vivo microperfusion experiments indicate that calcium absorption by the proximal tubule depends on more than one transport mechanism. We have observed that net calcium flux is affected by changes in calcium ion activity (even with constant total calcium concentration) and in transepithelial voltage.
Karol Bomsztyk, F. S. Wright
openaire +2 more sources
Endocytic Receptors in the Renal Proximal Tubule
Physiology, 2012Protein reabsorption is a predominant feature of the renal proximal tubule. Animal studies show that the ability to rescue plasma proteins relies on the endocytic receptors megalin and cubilin. Recently, studies of patients with syndromes caused by dysfunctional receptors have supported the importance of these for protein clearance of human ...
Christensen, Erik Ilsø +4 more
openaire +3 more sources
Degradation and transport of AVP by proximal tubule
American Journal of Physiology-Renal Physiology, 1987High-performance liquid chromatography (HPLC) analysis revealed that [3,4,5-3H-Phe3,Arg8]vasopressin ([3H]AVP) was not degraded by isolated renal brush-border membranes or by a cortical lysosomal fraction in vitro; however, in the presence of 1 mM reduced glutathione, [3H]AVP was degraded by both preparations.
Carone, F A +2 more
openaire +4 more sources
Chloride Transport in the Proximal Renal Tubule
Annual Review of Physiology, 1988Our knowledge of chloride transport along the nephron has greatly expanded. Whereas for a long time it was assumed that chloride ions were reabsorbed entirely passively with sodium--the "mendicant" role of chloride, more recent studies suggest that several distinct reabsorptive transport mechanisms operate in parallel.
L. Schild +5 more
openaire +4 more sources
The Proximal Tubule and the Podocyte in Cystinosis
Nephron, 1973The belief that the swan-neck lesion or the Fanconi syndrome in cystinosis are related to the accumulation of cystine in epithelium of the proximal tubule is questioned.
openaire +3 more sources
cAMP-Adenosine Pathway in the Proximal Tubule
The Journal of Pharmacology and Experimental Therapeutics, 2006The "extracellular cAMP-adenosine pathway" refers to the conversion of cAMP to AMP by ecto-phosphodiesterase, followed by metabolism of AMP to adenosine by ecto-5'-nucleotidase, with all the steps occurring in the extracellular compartment. This study investigated whether the extracellular cAMP-adenosine pathway exists in proximal tubules.
Raghvendra K. Dubey +6 more
openaire +3 more sources
Potassium channels in Necturus proximal tubule
American Journal of Physiology-Renal Physiology, 1987Potassium channels from the apical and basolateral membranes of Necturus proximal tubule were studied using the patch-clamp technique. The conductance of the basolateral channel was dependent on the pipette K+ concentration (apparent Km, 65.5 mM K+; maximum channel conductance, 49.8 pS). The permeability ratio (PK+/PNa+) was approximately 10:1.
Gerhard Giebisch, K. Kawahara, M. Hunter
openaire +3 more sources
Dopamine receptors in the proximal tubule of the rabbit
American Journal of Physiology-Renal Physiology, 1984Our laboratory has characterized dopamine receptors in glomeruli and tubular homogenates. Since the heterogeneity of kidney homogenates limits the interpretation of these studies, the [3H]haloperidol binding site and adenylate cyclase sensitivity to dopamine were studied in the isolated proximal convoluted tubule and pars recta of the rabbit kidney ...
Robin A. Felder +3 more
openaire +3 more sources
1994
The morphology of the proximal tubule cells was covered briefly in Chapter 2, but will be considered in more detail here. The proximal tubule is divisible into the convoluted portion, or pars convoluta, which begins immediately behind the glomerulus, and the straight portion, or pars recta, which passes into the medulla to become the loop of Henle. The
openaire +2 more sources
The morphology of the proximal tubule cells was covered briefly in Chapter 2, but will be considered in more detail here. The proximal tubule is divisible into the convoluted portion, or pars convoluta, which begins immediately behind the glomerulus, and the straight portion, or pars recta, which passes into the medulla to become the loop of Henle. The
openaire +2 more sources