Results 321 to 330 of about 611,505 (395)

GLP‐1RA use improves outcomes post partial nephrectomy in T2DM patients with RCC: A TriNetX study

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives The purpose of this study is to investigate the impact of Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) use on 90‐day postoperative outcomes and overall survival following partial nephrectomy (PN) for renal cell carcinoma (RCC), where type 2 diabetes mellitus (T2DM) is a common comorbidity.
Sam Kwon, Fiona Wardrop, Diego Gonzalez, Francis Ryan, Liza Khutsishvili, Rollins Turner, Mohammad Ghassab Deameh, Michael J. Whalen   +7 more
wiley   +1 more source

Proximal tubule hypertrophy and hyperfunction: a novel pathophysiological feature in disease states. [PDF]

Clin Kidney J
Kanbay M, Copur S, Guldan M, Ozbek L, Hatipoglu A, Covic A, Mallamaci F, Zoccali C.   +7 more
europepmc   +1 more source

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

ASK1 limits kidney glucose reabsorption, growth, and mid-late proximal tubule KIM-1 induction when diabetes and Western diet are combined with SGLT2 inhibition. [PDF]

Am J Physiol Renal Physiol
Crespo-Masip M, Goodluck HA, Kim YC, Oe Y, Roach AM, Kanoo S, Lopez N, Zhang H, Badal SS, Vallon V.   +9 more
europepmc   +1 more source

Inhaled Halogen‐Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Mechanisms of lung‐heart‐kidney interaction in inducing organ injury after chemical inhalation. Acute exposure to halogen gases causes extensive lung injury and acute cardiac damage leading to fatalities. Formation of highly reactive halogenated molecules in the pulmonary bed and their circulation resulting in oxidative stress and inflammation was ...
Juan Xavier Masjoan Juncos, Ahmed Zaky, Wesam Nasser, Amber J. Johns, Iram Zafar, Gajanan R. Jadhav, Jeremy B. Foote, Aftab Ahmad, Anupam Agarwal, Shama Ahmad   +9 more
wiley   +1 more source

Yapping at the autophagy door? The answer is flowing in the kidney proximal tubule. [PDF]

Autophagy
Claude-Taupin A, Terzi F, Codogno P, Dupont N.   +3 more
europepmc   +1 more source

Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease. [PDF]

Nat Commun
Gujarati NA, Frimpong BO, Zaidi M, Bronstein R, Revelo MP, Haley JD, Kravets I, Guo Y, Mallipattu SK.   +8 more
europepmc   +1 more source

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells. [PDF]

PLoS Pathog
Lorentzen EM, Henriksen S, Rinaldo CH.
europepmc   +1 more source

Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury.

Am J Physiol Renal Physiol
McElliott MC, Telang AC, Ference-Salo JT, Al-Suraimi A, Chowdhury M, Otto EA, Soofi A, Dressler GR, Beamish JA.   +8 more
europepmc   +1 more source

Renal Proximal Tubule Cell-Specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed a Western Diet. [PDF]

Arterioscler Thromb Vasc Biol
Amioka N, Franklin MK, Kukida M, Zhu L, Moorleghen JJ, Howatt DA, Katsumata Y, Mullick AE, Yanagita M, Martinez-Irizarry MM, Sandoval RM, Dunn KW, Sawada H, Daugherty A, Lu HS.   +14 more
europepmc   +1 more source