Results 211 to 220 of about 99,225 (351)

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

Suggestions for attenuation of renal ischemia reperfusion injury based on mechanisms involved in epithelial cells damages [PDF]

Journal of Nephropharmacology, 2015
Tavafi Majid
doaj  

DNA damage in proximal tubules triggers systemic metabolic dysfunction through epigenetically altered macrophages. [PDF]

Nat Commun
Nishimura ES, Hishikawa A, Nakamichi R, Akashio R, Chikuma S, Hashiguchi A, Yoshimoto N, Hama EY, Maruki T, Itoh W, Yamaguchi S, Yoshino J, Itoh H, Hayashi K.   +13 more
europepmc   +1 more source

Ceramide-1-Phosphate as a Potential Regulator of the Second Sodium Pump from Kidney Proximal Tubules by Triggering Distinct Protein Kinase Pathways in a Hierarchic Way. [PDF]

Curr Issues Mol Biol, 2022
Cabral LMP, Almeida FG, Grelle GMRS, Vieyra A, Caruso-Neves C, Einicker-Lamas M.   +5 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Sodium-glucose cotransporter 2 inhibitors ameliorate glutathione cysteine ligase modifier-mediated oxidative stress and subsequent ferroptosis in proximal tubules of diabetic kidney disease. [PDF]

Redox Rep
Tsai YC, Huang JC, Yu PS, Kuo MC, Wu LY, Chang WA, Hwang SJ, Hsu YL.   +7 more
europepmc   +1 more source

Comparison of the Impact of VRP-034 and Polymyxin B upon Markers of Kidney Injury in Human Proximal Tubule Monolayers In Vitro [PDF]

Keith Pye, Elena Tasinato, Siannah Shuttleworth, Claire Devlin, Colin Brown   +4 more
openalex   +1 more source

D ₃ Dopamine Receptor Directly Interacts With D ₁ Dopamine Receptor in Immortalized Renal Proximal Tubule Cells [PDF]

, 2006
Chunyu Zeng, Zheng Wang, Hewang Li, Peiying Yu, Shaopeng Zheng, Lijuan Wu, Laureano D. Asico, Ulrich Hopfer, Gilbert M. Eisner, Robin A. Felder, Pedro A. José   +10 more
openalex   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

A key role of AT_1a receptors and Na⁺/H⁺ exchanger 3 in the proximal tubules in angiotensin II-induced and two-kidney, one-clip Goldblatt hypertension. [PDF]

Am J Physiol Renal Physiol
Li XC, Hassan R, Zhuo JL.
europepmc   +1 more source