Results 241 to 250 of about 99,225 (351)

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Guided Cavity Preparation to Access an Invagination and Preserve Pulp Vitality of an Immature Maxillary Lateral Incisor With Type IIIa Dens Invaginatus: Technical Overview and a Case Report With 3‐Year Follow‐Up

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Dens invaginatus (DI) is a developmental anomaly often associated with caries and periapical pathosis. This report describes guided access and filling of an infected invagination in a maxillary lateral (tooth #22) with long‐term preservation of pulp vitality.
Francesc Abella Sans   +4 more
wiley   +1 more source

YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis

open access: gold, 2020
Ada Admin   +7 more
openalex   +1 more source

Retrospective comparison of the clinical effects of oral semaglutide and SGLT2 inhibitors treatment in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This retrospective study compared oral semaglutide and SGLT2 inhibitors in patients with type 2 diabetes over 6 months. Both treatments significantly reduced HbA1c, body weight, and fat mass. Although the reduction in fat mass was comparable, changes in skeletal muscle mass tended to be less favorable with SGLT2 inhibitors than with oral semaglutide ...
Yasuhiro Omori   +6 more
wiley   +1 more source

Selective inhibition of arginase-2 in endothelial cells but not proximal tubules reduces renal fibrosis. [PDF]

open access: yesJCI Insight, 2020
Wetzel MD   +6 more
europepmc   +1 more source

Self‐Adhesive Flowable Resin Composites—Are We Going Somewhere?

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To map laboratory/clinical evidence on self‐adhesive flowable resin composites (SAFRCs), tracing their chemical evolution, performance, and behavior, and to identify gaps that must be addressed to drive their optimization. Overview A comprehensive literature search was performed in PubMed/MEDLINE, Scopus, and LILACS without language ...
António H. S. Delgado   +4 more
wiley   +1 more source

Effect of Different Airborne‐Particle Abrasion Strategies on Dentin Bond Strength: An In Vitro Study

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To assess the influence of dentin airborne‐particle abrasion techniques on the microtensile bond strength, using two adhesive strategies (self‐etch and etch&rinse). Materials and Methods Twenty molars were assigned to two groups (n = 10) according to the bonding system (Clearfil SE Bond or Optibond FL), divided into four parts and ...
Rui I. Falacho   +7 more
wiley   +1 more source

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