Results 291 to 300 of about 99,225 (351)

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, Volume 38, Issue 7, 2 February 2026.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

GLP‐1RA use improves outcomes post partial nephrectomy in T2DM patients with RCC: A TriNetX study

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives The purpose of this study is to investigate the impact of Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) use on 90‐day postoperative outcomes and overall survival following partial nephrectomy (PN) for renal cell carcinoma (RCC), where type 2 diabetes mellitus (T2DM) is a common comorbidity.
Sam Kwon, Fiona Wardrop, Diego Gonzalez, Francis Ryan, Liza Khutsishvili, Rollins Turner, Mohammad Ghassab Deameh, Michael J. Whalen   +7 more
wiley   +1 more source

Fructose reabsorption by rat proximal tubules: role of Na⁺-linked cotransporters and the effect of dietary fructose.

Am J Physiol Renal Physiol, 2019
Gonzalez-Vicente A, Cabral PD, Hong NJ, Asirwatham J, Saez F, Garvin JL.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Androgens augment proximal tubule transport

American Journal of Physiology-Renal Physiology, 2004
The proximal tubule contains an autonomous renin-angiotensin system that regulates transport independently of circulating angiotensin II. Androgens are known to increase expression of angiotensinogen, but the effect of androgens on proximal tubule transport is unknown.
Albert, Quan, Sumana, Chakravarty, Jian-Kang, Chen, Jian-Chun, Chen, Samer, Loleh, Neel, Saini, Ray C, Harris, Jorge, Capdevila, Raymond, Quigley   +8 more
openaire   +2 more sources

The Renal Proximal Tubule

1979
Methodologic as well as conceptual progress during the past decade has made it possible for renal physiologists to “peek” inside the epithelial “black box” of renal tubular function with a greater degree of confidence than ever before. Among the more important developments have been: (1) evolution of the fluid mosaic model of plasma membrane structure (
M, Silverman, R J, Turner
openaire   +2 more sources

Potassium channels in Necturus proximal tubule

American Journal of Physiology-Renal Physiology, 1987
Potassium channels from the apical and basolateral membranes of Necturus proximal tubule were studied using the patch-clamp technique. The conductance of the basolateral channel was dependent on the pipette K+ concentration (apparent Km, 65.5 mM K+; maximum channel conductance, 49.8 pS). The permeability ratio (PK+/PNa+) was approximately 10:1.
K, Kawahara, M, Hunter, G, Giebisch
openaire   +2 more sources

Disorders of the Renal Proximal Tubule

Nephron Physiology, 2010
Following glomerular filtration, the bulk of solutes are reabsorbed in the proximal tubule to prevent excessive losses of vital metabolites. In this nephron segment, reabsorption is largely active via dedicated transporters. Hereditary defects in proximal tubular function are characterized by malabsorption affecting amino acids, glucose, potassium ...
Bokenkamp, A., Ludwig, M.
openaire   +4 more sources

Water Permeability in Rat Proximal Tubules

Acta Physiologica Scandinavica, 1970
AbstractThe diffusional water permeability in rat proximal tubules was studied in microperfusion experiments with triturated water. The perfusion solutions were chosen either to give no net flux or a net water flux in either direction. The diffusional water permeability at zero net water flux was 564. 10‐‐5 cm/sec.
E, Persson, H R, Ulfendahl
openaire   +2 more sources