Results 151 to 160 of about 760,132 (338)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Interference of Continuous Renal Replacement Therapy on PiCCO Hemodynamic Monitoring: A Case Report

Clinical Case Reports
The proximity of the central venous and dialysis catheters during continuous renal replacement therapy can interfere with Pulse Index Continuous Cardiac Output hemodynamic measurements. Adjusting catheter placement or temporarily pausing continuous renal
Xiaohua Lin, Zhijun Suo, Xuan Liu, Haigang Zhang, Yunsheng Yuan   +4 more
doaj   +1 more source

Measuring the Compactness of Political Districting Plans [PDF]

The United States Supreme Court has long recognized compactness as an important principle in assessing the constitutionality of political districting plans. We propose a measure of compactness based on the distance between voters within the same district
Richard T. Holden, Roland G. Fryer, Jr
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Forest fragmentation and heterogeneity shape the occurrence of woodpecker species in Central Europe

Scientific Reports
The study investigates the impact of fragmentation metrics and other forest characteristics on the occurrence and richness of woodpecker species in 163 forest patches in Southern Poland. Generalised linear mixed models were used to estimate the influence
Michał Bełcik, Bartłomiej Woźniak, Piotr Skórka   +2 more
doaj   +1 more source

AIR POLLUTION TOLERANCE INDEX OF WHEAT AND RICE IN THE PROXIMITY OF GAS BASED POWER PLANT

, 2021
Priya Choudhary, Shakeel A. Khan, Ambrina Sardar Khan, Sandeep Kumar, Lal Chand Malav   +4 more
openalex   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Three-Dimensional Field Investigation of Mixing Dynamics in a River Confluence Using a Mixing Proximity Index (Mpi) [PDF]

Suin Choi, Seogyeong Lee, Dongsu Kim, Il Won Seo, Yongmuk Kang, by Sangjo Jeong   +5 more
openalex   +2 more sources

greenR: An open-source framework for quantifying urban greenness

Ecological Indicators
How do we quantify the levels of greenness within urban street networks? Numerous attempts to quantify this factor have been made through survey methodologies, remote sensing data, and street view imagery. The results are promising, but are often limited
Sachit Mahajan
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source