Results 141 to 150 of about 760,132 (338)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Comments on the radio spectrum of HB 3
It has recently been suggested that the radio spectrum of the Galactic supernova remnant HB 3 shows flattening at higher frequencies (above about 1 GHz).
Green, D. A.
core +2 more sources
Associations of Maternal Educational Level, Proximity to Green Space During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts [PDF]
Tim Cadman +50 more
openalex +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Revisiting the Index Construction of Proximity Graph-Based Approximate Nearest Neighbor Search [PDF]
Shuo Yang +7 more
openalex +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Voltage stability ensures reliable and efficient power transmission to end-users, making it essential for power system efficiency. Dynamic load changes and rising power requirements might cause voltage instability and strain performance.
Hasan Saeed Qazi +5 more
doaj +1 more source
An Improved Algorithm for Fast K-Word Proximity Search Based on Multi-component Key Indexes [PDF]
Alexander B. Veretennikov
openalex +1 more source

