Results 131 to 140 of about 180,110 (333)

Risk of transmission of SARS-CoV-2 on international flights, a retrospective cohort study using national surveillance data in England

BMC Infectious Diseases
Background It is not yet fully understood to what extent in-flight transmission contributed to the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Joshua Howkins, Simon Packer, Eleanor Walsh, Deepti Kumar, Obaghe Edeghere, Matthew Hickman, Isabel Oliver   +6 more
doaj   +1 more source

The return to the technological frontier: The conditional effect of plants’ R&D on their productivity in Finnish manufacturing

This paper examines, through the use of plant-level data, whether R&D’s productivity impact is contingent on the distance of a plant’s productivity from the industry’s technological frontier. R&D is specified as an accumulated stock from R&D investments.
Böckerman, Petri, Eero, Lehto, Huovari, Janne   +2 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Stability analysis and voltage improvement in DG-integrated distribution networks using VCPI-based critical buses and lines detection considering uncertain power factor

Ain Shams Engineering Journal
Voltage stability ensures reliable and efficient power transmission to end-users, making it essential for power system efficiency. Dynamic load changes and rising power requirements might cause voltage instability and strain performance.
Hasan Saeed Qazi, Zia Ullah, Ahmad Alferidi, Mohammed Alsolami, Badr Lami, Syed Muhammad Abrar Akber   +5 more
doaj   +1 more source

The Index, Senior Issue, 1914: Portraits of Leon Rowland and Gladys Martin

, 1914
Searchable PDFIn this Senior Issue of the 1914 Index, the portraits of Leon Rowland and Gladys Martin can be found in proximity to each other. The two would marry on June 17, 1915. They would go on to serve as missionaries in Southern India.

core  

Labour and technology at the time of Covid 19. Can artificial intelligence mitigate the need for proximity?

, 2021
What’s this paper about: 1) Novel evidence of the proximity on the workplace in Italy; occupational and sectoral requirements of proximity; geographical distribution of the index of proximity; 2) The potential of artificial intelligence (AI) in reducing ...
Sergio, Scicchitano
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source