Results 131 to 140 of about 760,132 (338)

Spatial structure and mechanism of cross-city patient mobility network in the Yangtze River economic belt of China

open access: yesJournal of Urban Management
Cross-city patient mobility reflects the geographic mismatch in medical resources, posing significant challenges for healthcare accessibility and equitable resource allocation.
Bowen Xiang   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Studi Efektifitas Indikator Kestabilan Tegangan Pada Model Dinamis Sistem Tenaga Listrik

open access: yesSemesta Teknika, 2016
The paper presents the effectiveness of voltage stability indices for dynamic power system modelling study in providing information about the proximity of voltage collapse in power system.
Muhammad Nizam
doaj  

Spatial proximity and distance travelled: commuting versus non-commuting trips in Flanders [PDF]

open access: yes, 2011
This paper examines the relationship between daily travel distance and spatial characteristics in Flanders (and partly also in Brussels), in the north of Belgium.
Boussauw, Kobe, Witlox, Frank
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Risk of transmission of SARS-CoV-2 on international flights, a retrospective cohort study using national surveillance data in England

open access: yesBMC Infectious Diseases
Background It is not yet fully understood to what extent in-flight transmission contributed to the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Joshua Howkins   +6 more
doaj   +1 more source

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