Results 111 to 120 of about 760,132 (338)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Proximity and linkages among coalition participants: a new voting power measure applied to the International Monetary Fund [PDF]
Voting power methodology offers insights to understand coalition building in collective decision making. Using cooperative game theory, Banzhaf (1965) developed an index to capture the numerical importance of voters in coalition building.
Gatarek, Lukasz +2 more
core
Gender homophily from spatial behavior in a primary school: a sociometric study
, 2013 We investigate gender homophily in the spatial proximity of children (6 to 12 years old) in a French primary school, using time-resolved data on face-to-face proximity recorded by means of wearable sensors.
Barrat, A. +4 more
core +3 more sources
The proximate type and λ-proximate type of an entire Dirichlet series with index-pair (p, q)
Journal of Mathematical Analysis and Applications, 1985 Let \(f(s)=\sum^{\infty}_{n=1}a_ n\exp (s\lambda_ n)\) where \(s=\sigma +it\), \(0\leq \lambda_ ...
openaire +2 more sources
Cast index in predicting outcome of proximal pediatric forearm fractures
Indian Journal of Orthopaedics, 2015 Many pediatric forearm fractures can be treated in plaster following closed reduction. The cast index (CI, a ratio of anteroposterior to lateral internal diameters of the cast at the fracture site) is a simple, reliable marker of quality of molding and a CI of >0.8 correlates with increased risk of redisplacement. Previously, CI has been applied to all
Sheikh, Hassaan Qaiser +2 more
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
PROXIMATE COMPOSITION AND PALM JUICE GLYCEMIC INDEX
Biospecies, 2020 Penelitian ini bertujuan untuk mengevaluasi komposisi proksimat dan nilai indeks glikemik nira aren. Analisis kadar air menggunakan metode oven, protein menggunakan metode semimikro kjeldhal, kadar abu menggunakan metode thermografimetri, dan lemak menggunakan metode ekstruksi langsung dengan alat soxhlet, karbohidrat menggunakan metode by difference ...
Solang, Margaretha +2 more
openaire +1 more source