Results 51 to 60 of about 191,364 (306)
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Genomic supremacy: the harm of conflating genetic ancestry and race
Human Genomics, 2022 Background Recent studies have reignited the tinderbox of debate surrounding the use of race and ancestry in medicine. These controversial studies have argued for a strong correlation between genetic ancestry and race, justifying continued use of genetic
Jessica P. Cerdeña +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The ‘Little Ice Age’ in the Southern Hemisphere in the context of the last 3000 years : Peat-based proxy-climate data from Tierra del Fuego [PDF]
, 2014 DM’s research (at Department of Earth Sciences, Uppsala University) was supported through a European Community Marie Curie Fellowship (Contract HPMF-CT-2000-01056).Peer ...
Brain, Sally A. +4 more
core +2 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Quieting the Sharholders\u27 Voice: Empirical Evidence of Pervasive Bundling in Proxy Solicitations [PDF]
, 2016 The integrity of shareholder voting is critical to the legitimacy of corporate law. One threat to this process is proxy “bundling,” or the joinder of more than one separate item into a single proxy proposal. Bundling deprives shareholders of the right to
Cox, James D. +3 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Geochemistry, Geophysics, Geosystems, 2021 Enamel as hardest biological tissue remains unaltered for millions of years and is therefore an excellent archive for studies on paleodiet, paleoecology, paleoclimate, paleoenvironment, biomechanical, and evolutionary studies.
Nataniel Białas +5 more
doaj +1 more source
Authority and Interest in the Theory of Right [PDF]
, 2019 I suggest a new role for authority and interest in the theory of right: Rights can be explicated as sets of prohibitions, permissions and commands, and they must be justified by interests.
Katharina, Nieswandt
core +1 more source
Frontiers in Earth Science, 2022 The history of the nitrogen cycle on Earth is linked to the redox evolution of the surface environment. Many nitrogen cycle fluxes are microbially mediated, and the particular fluxes operating at any given time in an ecosystem depend on the presence, absence or abundance of oxygen.
Benjamin W. Johnson +2 more
openaire +2 more sources