Results 81 to 90 of about 159,476 (341)

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

Use of Whole Genome Phylogeny and Comparisons in the Development of a Multiplex-PCR Assay to Identify Sequence Type 36 Vibrio parahaemolyticus [PDF]

, 2015
Vibrio parahaemolyticus sequence type (ST) 36 strains that are native to the Pacific Ocean have recently caused multi-state outbreaks of gastroenteritis linked to shellfish harvested from the Atlantic Ocean.
Cooper, Vaughn S., Hall, Jeffrey A., Ilyas, Saba, Jones, Stephen H., Siwakoti, Puskar, Whistler, Cheryl A., Xu, Feng   +6 more
core   +1 more source

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Therapeutic potential of platelet-rich plasma in diseases and injuries of the large joints

Медицинский совет, 2019
Numerous non-surgical and surgical procedures have been proposed to treat injuries and diseases of the large joints. Any small bone and cartilage defect can progress quite quickly and cause osteoarthritis to develop in many joints without proper ...
G. A. Airapetov
doaj   +1 more source

Shortest known prion protein allele in highly BSE-susceptible lemurs [PDF]

, 2000
We describe the shortest prion protein allele known to date. Surprisingly, it is found as a polymorphism exactly in a species (prosimian lemurs) which seems highly susceptible to oral infection with BSE-derived prions. The truncation of the prion protein
Gilch, S., Schätzl, H. M., Spielhaupter, C.   +2 more
core   +1 more source

Enhanced Sensitivity of a Modified Quaking‐Induced Conversion Diagnostic Test for the Broad Detection of Sporadic and Inherited Prion Diseases: A Retrospective Study

Annals of Neurology, EarlyView.
Objective Quaking‐induced conversion (QuIC) tests, which detect prion‐seeding activity in cerebrospinal fluid (CSF), have markedly advanced the antemortem diagnosis of prion diseases such as Creutzfeldt‐Jakob disease (CJD). These tests provide high diagnostic accuracy and enable timely differentiation from other rapidly progressive neurodegenerative ...
Jennifer Myskiw, Rebecca Fox, Dominic M.S. Kielich, Lise Lamoureux, Melanie Leonhardt, Olivia Nykvist, Jessy A. Slota, Kristen Avery, Clark Phillipson, Kathy Frost, Sharon Simon, Brian S. Appleby, Ben A. Bailey‐Elkin, Stephanie A. Booth   +13 more
wiley   +1 more source

HISTOPATHOLOGICAL STUDY OF PLATELETE RICH PLASMA FOR TREATMENT OF INDUCED CUTANEOUS ULCER IN DIABETIC RABBITS INDUCED BY STREPTOZOTOCIN [PDF]

Basrah Journal of Veterinary Research, 2019
The present study investigates the effect of platelets rich plasma (PRP) on the healing of skin ulcers in rabbits in which diabetes mellitus (DM) was induced using Streptozotocin. The study was applied on 12 adult rabbits of both sexes with a mean weight
doaj   +1 more source

Analysis of platelet-rich plasma extraction variations in platelet and blood components between 4 common commercial kits [PDF]

, 2017
Background: Platelet-rich plasma (PRP) has been extensively used as a treatment in tissue healing in tendinopathy, muscle injury, and osteoarthritis. However, there is variation in methods of extraction, and this produces different types of PRP. Purpose:
Bulsara, MK, Fitzpatrick, J, McCrory, PR, Richardson, MD, Zheng, MH   +4 more
core   +2 more sources

Redox‐Responsive Mitochondrial Delivery from Functionalized Vascular Stent Surfaces

Advanced NanoBiomed Research, EarlyView.
A redox‐responsive stent surface is engineered to deliver functional mitochondria in response to oxidative stress. Upon exposure to reactive oxygen species, grafted mitochondria are released, internalized by vascular cells, and restore mitochondrial function under stress.
Fang Tang, Brandon C. Applewhite, Bowen Wang, Bin Jiang   +3 more
wiley   +1 more source

Pattern Research Project: An Investigation of The Pattern And Printing Process - Koi Wallpaper [PDF]

, 2017
2017 Pattern Research Project Thao Khia - Koi The Pattern Research Project involves research and analysis of contemporary patterns found in the textiles and wallcoverings of the built interior environment. Patterns use motif, repetition, color, geometry,
Khia, Thao
core   +1 more source