Results 41 to 50 of about 51,239 (287)

Increased (Pro)renin Receptor Expression in the Hypertensive Human Brain

Frontiers in Physiology, 2020
Overactivation of the renin-angiotensin system (RAS) – a central physiological pathway involved in controlling blood pressure (BP) – leads to hypertension.
Minhazul Mohsin, Minhazul Mohsin, Lucas A. C. Souza, Lucas A. C. Souza, Simindokht Aliabadi, Simindokht Aliabadi, Caleb J. Worker, Caleb J. Worker, Silvana G. Cooper, Silvana G. Cooper, Sanzida Afrin, Sanzida Afrin, Yuki Murata, Zhenggang Xiong, Yumei Feng Earley, Yumei Feng Earley   +15 more
doaj   +1 more source

Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts

Scientific Reports, 2021
The (pro)renin receptor (PRR) is a multifunctional integral membrane protein that serves as a component of the vacuolar H+-ATPase (V-ATPase) and also activates (pro)renin.
Jonathan B. Murray, Christy Mikhael, Guanghong Han, Lorraine Perciliano de Faria, Wellington J. Rody, L. Shannon Holliday   +5 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Sustainable development goals in tourism research

Discover Sustainability
Tourism has a significant impact on the society’s development. This study aims to analyze the integration of the sustainable development goals (SDGs) in various tourism areas through a bibliometric analysis and a systematic review of the literature ...
Alexandra Lavaredas, Filipa Campos, Giovana Goretti Feijó Almeida, Francisco Dias, Paulo Almeida   +4 more
doaj   +1 more source

ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression

Cancer Management and Research, 2020
Kankan Zhao,* Mengchuan Wang,* Aiguo Wu Department of General Surgery, Zhujiang Hospital, The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510282, People’s Republic of China*These authors contributed equally to this ...
Zhao K, Wang M, Wu A
doaj  

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner, Ellen M. Cody, Prasad Devarajan, Bin Huang, Chen Chen, Dominic Sinibaldi, Madhu Ramaswamy, Jacob Knagenhjelm, Frederick Jones, Philip Z. Brohawn, Raj Tummala, Catharina Lindholm, Wendy I. White   +12 more
wiley   +1 more source

Trigonelline, a Fenugreek Bioactive compound protects Heart tissue against alcohol intoxication: An in-vivo study focusing on antioxidant perspective

Journal of Ayurveda and Integrative Medicine
Background: Trigonella foenum-graecum, commonly known as fenugreek and it is used as a spice. It has antioxidant, anti-diabetic, antilipedemic and other pharmocological properties.
Meesala Guru Sekhar, Kondeti Ramudu Shanmugam, Inavolu Srinivasa Chakrapani   +2 more
doaj   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Factors Associated With Unhealthy Snacks Consumption Among Adolescents in Iran’s Schools [PDF]

International Journal of Health Policy and Management, 2017
Background Well-informed interventions are needed if school-based health promotion is to be effective. Amongother aims, the Iranian Health Promoting School (IHPS) program that was launched in 2011, has an important aimof promoting dietary behaviors of ...
Vahid Yazdi Feyzabadi, Nastaran Keshavarz Mohammadi, Nasrin Omidvar, Akram Karimi-Shahanjarini, Saharnaz Nedjat, Arash Rashidian   +5 more
doaj   +1 more source

Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin-angiotensin system.

American Journal of Physiology. Heart and Circulatory Physiology, 2019
Deletion of the prorenin receptor (PRR) in adipose tissue elevates systolic blood pressure (SBP) and the circulating soluble form of PRR (sPRR) in male mice fed a high-fat (HF) diet. However, sex differences in the contribution of adipose-PRR and sPRR to

semanticscholar   +1 more source