Results 51 to 60 of about 47,105 (312)

Trigonelline, a Fenugreek Bioactive compound protects Heart tissue against alcohol intoxication: An in-vivo study focusing on antioxidant perspective

Journal of Ayurveda and Integrative Medicine
Background: Trigonella foenum-graecum, commonly known as fenugreek and it is used as a spice. It has antioxidant, anti-diabetic, antilipedemic and other pharmocological properties.
Meesala Guru Sekhar, Kondeti Ramudu Shanmugam, Inavolu Srinivasa Chakrapani   +2 more
doaj   +1 more source

Factors Associated With Unhealthy Snacks Consumption Among Adolescents in Iran’s Schools [PDF]

International Journal of Health Policy and Management, 2017
Background Well-informed interventions are needed if school-based health promotion is to be effective. Amongother aims, the Iranian Health Promoting School (IHPS) program that was launched in 2011, has an important aimof promoting dietary behaviors of ...
Vahid Yazdi Feyzabadi, Nastaran Keshavarz Mohammadi, Nasrin Omidvar, Akram Karimi-Shahanjarini, Saharnaz Nedjat, Arash Rashidian   +5 more
doaj   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Continuous‐Flow Microfluidic Synthesis Enhances C2+ Selectivity for Cu2O Catalysts

Advanced Science, EarlyView.
Microfluidic devices are used to prepare Cu2O nanoparticles under laminar flow conditions, which exhibit enhanced selectivity in the CO2‐to‐C2+ reaction due to their nanoporosity and high defect concentration. Cu2O prepared using standard solution methods displays decreased CO2‐to‐C2+ selectivity due to the absence of similar properties. Altogether, we
Carlota Casas, Anh Tuan Ngo, João Pedro Vale, Ona Falcó, Gerard Martí, Mohamed Amazian, Júlia Mayans, Sònia Estradé, Marcos Gil‐Sepulcre, Teresa Andreu, Francesca Peiró, Tiago Sotto Mayor, Lluís Yedra, Jordi García‐Antón, Josep Puigmartí‐Luis, Xavier Sala, Roc Matheu   +16 more
wiley   +1 more source

Learning to Drive Backwards: Understanding Populist Radical Right Policy Diffusion

International Review of Public Policy
The rise of the populist radical right (PRR) has generated significant academic interest. As they move from the fringes to power, PRR parties tend to employ similar strategies to achieve similar public policy priorities.
Alexander Mesarovich
doaj   +1 more source

A hydroponics based high throughput screening system for Phytophthora root rot resistance in chickpea (Cicer arietinum L.)

Plant Methods, 2019
Background Phytophthora root rot (PRR) caused by P. medicaginis is a major soil borne disease in chickpea growing regions of Australia. Sources of resistance have been identified in both cultivated and wild Cicer species.
Amritha Amalraj, Julian Taylor, Tim Sutton   +2 more
doaj   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Renal expressions of (pro)renin receptor (PRR).

, 2019
(A) mRNA and PRR protein (B) in non-diabetic control mice (n = 6 each group), and streptozotocin (STZ)-induced diabetic mice (DM; n = 6) treated with PRR shRNA (DM + PRR + shRNA; n = 6 each group), after eight weeks of STZ-induction of diabetes ...
Helmy M. Siragy (8082086), Safia Akhtar (8082083)   +1 more
core   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source