Results 141 to 150 of about 118,288 (291)
Clinical Pharmacology &Therapeutics, EarlyView.Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz +15 more
wiley +1 more source
Environmental and geomorphological drivers of frog diversity on islands worldwide
Ecography, EarlyView.Island biogeography models primarily rely on island physical features and isolation to explain their biodiversity patterns. While newer models have incorporated functional traits to understand plant distribution, few empirical studies have tried to disentangle geometric constraints from niche‐based processes to predict multiple diversity facets of ...
Raoni Rebouças +5 more
wiley +1 more source
The macroecology of immunity: predominant influence of climate on invertebrate immune response
Ecography, EarlyView.The immune system is the primary defense against parasites. With the ever‐increasing rate of disease, epidemiologic models considering geographic variation in immune responses could prove useful. Despite increasing interest in the macroecology of parasitism and infectious diseases, we know little about the macroecology of immune responses (i.e ...
Adam Z. Hasik +9 more
wiley +1 more source
Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications
Environmental Progress &Sustainable Energy, EarlyView.Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu +6 more
wiley +1 more source
Syndrome‐specific and familial imaging traits in juvenile absence epilepsy
Epilepsia, EarlyView.Abstract Objective Juvenile absence epilepsy (JAE) is an idiopathic generalized epilepsy characterized by absences, generalized tonic–clonic seizures, and cognitive difficulties. In contrast to juvenile myoclonic epilepsy (JME), where distinct functional and structural brain alterations are well established, it remains unclear whether comparable ...
Fenglai Xiao +15 more
wiley +1 more source
AI‐based localization of the epileptogenic zone using intracranial EEG
Epilepsia Open, EarlyView.Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida +5 more
wiley +1 more source
Energy Science &Engineering, EarlyView.Interpretable tree‐based models integrate microseismic, geological, and mining indicators to predict short‐term rockburst risk. SHAP analysis reveals the dominant role of energy‐related features and clarifies nonlinear factor interactions, enabling transparent and reliable early‐warning in deep coal mines.
Shuai Chen +4 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Food Biomacromolecules, EarlyView.Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source
Future Postharvest and Food, EarlyView.The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
wiley +1 more source