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Efficacy and Safety of Conventional and Biologic Therapies in Prurigo Nodularis: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Prurigo nodularis (PN) is a chronic, intensely pruritic skin disorder characterized by hyperkeratotic nodules and a debilitating itch–scratch cycle. Conventional therapies have limited efficacy and safety issues, while biologics have recently emerged as a promising alternative.
Lancz A +7 more
europepmc +2 more sources
Prurigo Simplex or “Itchy Red Bump” Disease: Review and Case Series
Prurigo simplex or “itchy red bump” disease is a controversial pruritic papular eruption. The objective of this study was to delineate the diagnostic criteria for this disease.
Joanna Wallengren
doaj +1 more source
Prurigo nodularis is an extremely pruritic skin condition as a result of chronic and vicious cycle of itching and scratching. It is rare in children. We report a case of a 4-year-old child with a background of poorly controlled atopic dermatitis with ...
Henrietta Albela, Kin Fon Leong
doaj +1 more source
Oral Alitretinoin for Patients with Refractory Prurigo
Background: prurigo is a chronic skin disorder associated with a history of chronic pruritus. The pathogenesis of prurigo is largely unknown and the treatment of prurigo is unsatisfactory and challenging.
Bo Young Chung +7 more
doaj +1 more source
Investigator’s Global Assessment of Chronic Prurigo: A New Instrument for Use in Clinical Trials
Chronic prurigo is a pruritic disease characterized by the development of pruriginous lesions due to scratching. The number of lesions is representative of the stage of the disease, while the presence of excoriations reflects the scratching activity. Aim
Claudia Zeidler +4 more
doaj +1 more source
Prurigo nodularis responding to intravenous immunoglobulins
Prurigo nodularis is a chronic skin disease, especially seen in middle-aged women adults. It is characterized by symmetric, pruritic hyperkeratotic nodules and papules on the extensor surfaces [1].
Koray Durmaz +3 more
doaj +1 more source
Correlation of serum IgE levels and clinical manifestations in patients with actinic prurigo [PDF]
BACKGROUND: Actinic prurigo is an idiopathic photodermatosis, the pathophysiology of which has been hypothesized to involve subtype IV type b (Th2) hypersensitive response, whereby IL4, IL5, and IL13 are secreted and mediate the production of B cells ...
Juan Carlos Cuevas-Gonzalez +4 more
doaj +1 more source
Clinical observation of a prurigo nodularis in a HIV-positive patient
The human immunodeficiency virus (HIV) is a globally spreading virus that represents one of the most serious social and health problems. The epidemic situation of HIV (human immunodeficiency virus) infection in the world and, in particular, in the ...
E. N. Efanova +2 more
doaj +1 more source
Introduction. The objective of this work is to document the epidemiological, clinical, and etiological features of prurigo in children. Methods. This is a descriptive and retrospective study done from January 2013 to September 2018 in the Dermatology ...
Bérénice Dégboé +11 more
doaj +1 more source
Biopsychosocial factors associated with prurigo nodularis in endogenous eczema
Background: Prurigo nodularis is a dermatological manifestation secondary to chronic scratching or picking on focal areas of the skin. Its pathogenesis remains poorly understood, and limited data has indicated its association with psychological factors ...
Choon Chiat Oh +3 more
doaj +1 more source

