Results 41 to 50 of about 9,731 (238)

A Case of Pembrolizumab‐Induced Pityriasis Lichenoides‐Like Eruption Treated Successfully With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Immune‐checkpoint inhibitors (ICIs) have revolutionised melanoma treatment but can often cause severe and long‐standing cutaneous immune‐related adverse events (cirAEs). We report a case of refractory pembrolizumab‐induced pityriasis lichenoides (PL)‐like eruption successfully treated with dupilumab, leading to rapid and sustained remission ...
Evangelos Christou, Sharon Edwards, Andrew Affleck   +2 more
wiley   +1 more source

An unusual case of multibacillary leprosy mimicking prurigo nodularis

Clinical Case Reports, 2020
Leprosy is a chronic infectious disease with a wide range of clinical manifestations. The early diagnosis of leprosy is a worldwide challenge. We present a case of leprosy with unusual severe pruritus and generalized excoriated papules and nodules.
Pedram Noormohammadpour, Kambiz Kamyab‐Hesari, Zahra Razavi, Nooshin Dolatyabi, Jafar Taghizadeh Fazli, Maryam Daneshpazhooh, Zeinab Nouri   +6 more
doaj   +1 more source

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]

, 2020
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos, Baldrich, Esther Serra, Herráez, L., Jáuregui, Ignacio, Martín-Santiago, Ana, Ortiz de Frutos, Javier, Sastre, Joaquin, Silvestre, Juan Francisco, Universitat Autònoma de Barcelona, Valero, Antonio   +9 more
core   +3 more sources

Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle, Claire Abasq‐Thomas, Claire Bocciarelli, Amélie Bourhis, Marina Alexandre, Belen Eguia, Laurent Misery, Numa Deydier   +7 more
wiley   +1 more source

Out‐of‐pocket expenditures in adult patients with prurigo nodularis in France

JEADV Clinical Practice, 2023
Background Chronic prurigo or prurigo nodularis is a severe condition with chronic pruritus and skin lesions. Current unnmet medical needs are numerous and generate a significant burden for the patients.
Laurent Misery, Christine Patras deCampaigno, Denis Jullien, Adrien Marquie, Sylvie Gabriel, Charles Taieb, Carle Paul   +6 more
doaj   +1 more source

Circulating plasma IL-13 and periostin are dysregulated type 2 inflammatory biomarkers in prurigo nodularis: A cluster analysis

Frontiers in Medicine, 2022
ImportancePrurigo nodularis (PN) is a chronic heterogeneous inflammatory skin disease.ObjectiveTo elucidate which components of type 2 inflammation are dysregulated systemically in PN.DesignWhole blood was obtained from PN patients with uncontrolled ...
Varsha Parthasarathy, Karen Cravero, Junwen Deng, Zhe Sun, Sarah M. Engle, Autum N. Auxier, Nathan Hahn, Jonathan T. Sims, Angela J. Okragly, Martin P. Alphonse, Shawn G. Kwatra   +10 more
doaj   +1 more source

A review of photodiagnostic investigations over 26 years:experience of the National Scottish Photobiology Service (1989-2015) [PDF]

, 2017
Background The Scottish Photobiology Service is the national referral pathway for patients with cutaneous photosensitivity diseases in Scotland. We reviewed the pattern of diagnosis of photosensitivity diseases and investigations performed between 1989 ...
Dawe, Robert, Ibbotson, Sally, Moseley, Harry, Naasan, Hannah   +3 more
core   +3 more sources

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Role of Substance P and Its Receptor Neurokinin 1 in Chronic Prurigo: A Randomized, Proof-of-Concept, Controlled Trial with Topical Aprepitant

Acta Dermato-Venereologica, 2017
Substance P (SP) and its receptor neurokinin 1 (NK1R) are thought to be involved in the pathogenesis of chronic prurigo. Here, we assessed SP serum levels, cutaneous NK1R expression, and the effects of topical aprepitant, an NK1R antagonist, in patients ...
Tatevik Ohanyan, Nicole Schoepke, Stefan Eirefelt, Gert Hoey, Witte Koopmann, Tomasz Hawro, Marcus Maurer, Martin Metz   +7 more
doaj   +1 more source

PRURIGO COMO MARCADOR CUTÂNEO DE INFECÇÃO PELO HTLV

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2014
Introdução: O prurigo ainda não foi definitivamente associado à infecção pelo HTLV. Entretanto, há relatos de casos com aparecimento dessas lesões anos antes de surgimento de Leucemia Linfoma de Células T do Adulto(LLTA), como pródromo da neoplasia ...
Tiago Silveira-Lima, Ana Paula Frade Lima Pinto, Tullia Cuzzi, Beatriz Moritz Trope   +3 more
doaj   +1 more source