Results 131 to 140 of about 6,645 (195)

Nemolizumab in prurigo nodularis up to 100 weeks: OLYMPIA LTE interim analysis.

Journal of the European Academy of Dermatology and Venereology, EarlyView.
BACKGROUND Prurigo nodularis (PN) is a neuroimmune skin disease characterized by the presence of chronic itch (≥6 weeks) and multiple white-pink papules, nodules and/or plaques.
F. Legat, S. Kwatra, Adam Reich, Serge Boulinguez, Athanasios Tsianakas, Maxwell Sauder, S. Barbarot, Jacek C. Szepietowski, C. Conrad, A. Pink, E. Weisshaar, L. Misery, M. Metz, V. Laquer, Raja K Sivamani, Gil Yosipovitch, D. Thaçi, L. Skov, Xiaoxiao Chen, Aliene Noda, Zarif K. Jabbar-Lopez, C. Piketty, Sonja Ständer   +22 more
semanticscholar   +2 more sources

Comorbidities and Healthcare Utilization in 4197 Patients With Prurigo Nodularis in Israel: A Cross-Sectional Population-Based Analysis.

International Journal of Dermatology, EarlyView.
BACKGROUND Prurigo nodularis patients face a significant burden of comorbidities, necessitating a comprehensive approach to care. We aimed to explore the association between prurigo nodularis, its comorbid conditions, and healthcare usage patterns ...
Y. Valdman-Grinshpoun, A. Zaga, A. Cohen, Y. Schonmann, T. Czarnowicki   +4 more
semanticscholar   +2 more sources

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Prurigo Nodularis Management

2016
Characterized by the clinical presentation of individual to multiple symmetrically distributed, hyperkeratotic, and intensely itchy papules and nodules, prurigo nodularis (PN) is a rare disease that emerges in patients with chronic pruritus due to continuous scratching over a long period of time.
Athanasios, Tsianakas, Claudia, Zeidler, Sonja, Ständer   +2 more
openaire   +2 more sources

Prurigo Nodularis: New insights into pathogenesis and novel therapeutics.

British Journal of Dermatology
Prurigo nodularis (PN) is an inflammatory skin condition characterized by intensely pruritic nodules on the skin. PN patients suffer from an intractable itch-scratch cycle leading to impaired sleep, psychosocial distress, and a significant disruption in ...
Viviane Liao, Hannah L Cornman, Emily Z. Ma, S. Kwatra   +3 more
semanticscholar   +1 more source

Long-term (68 weeks) administration of nemolizumab and topical corticosteroids for prurigo nodularis in patients aged ≥13 years: efficacy and safety data from a phase II/III study.

British Journal of Dermatology
BACKGROUND The biological therapy nemolizumab has been shown to improve the signs and symptoms of prurigo nodularis (PN) to a significantly greater extent than placebo over 16 weeks of treatment.
H. Yokozeki, H. Murota, T. Matsumura
semanticscholar   +1 more source

Prurigo nodularis: disease burden, clinical features and approach to management.

British Journal of Dermatology
Prurigo nodularis (PN) is a distinct, chronic inflammatory skin disease characterised by intensely pruritic, fibrotic nodular lesions. Despite continued progress in the field, lack of clarity regarding the definition of PN as a disease, clinical ...
S. Kwatra, M. Pereira, L. Misery, Nicholas K. Mollanazar, Parul Shah, Simmi Wiggins   +5 more
semanticscholar   +1 more source

Translating tissue expression of STAT 1, 3 and 6 in prurigo nodularis to clinical efficacy of oral tofacitinib - A prospective single-arm investigational study.

Indian Journal of Dermatology, Venereology and Leprology
Background Interleukin (IL)-4, IL-13, IL-17, IL-22 and IL-3 are overexpressed in prurigo nodularis (PN). They mediate their action via the Janus Kinase (JAK) Signal transducer and activator of transcription (STAT) pathway. Objectives Our aim was to study
K. Sardana, S. Mathachan, Aishwarya Muddebihal, Diksha Agrawal, Arvind Ahuja   +4 more
semanticscholar   +1 more source

Increased risk of psychiatric disease in patients with prurigo nodularis.

British Journal of Dermatology
Prurigo nodularis (PN) is a chronic skin disorder. Emerging, though limited, evidence suggests an association between PN and psychiatric comorbidities.
Salam Alfarsi, Andreas Recke, Evelyn Gaffal, J. P. Klein, H. Zirpel, K. Kridin, D. Thaçi, Henning Olbrich, K. Bieber, R. J. Ludwig   +9 more
semanticscholar   +1 more source

Improvement of Prurigo Nodularis With Erenumab.

JAMA dermatology
This case report describes a patient in her 50s with prurigo nodularis and itch at the elbows, which spread to all extremities, the trunk, and genital area.
M. Pereira, M. Metz
semanticscholar   +1 more source

Clinical Characteristics, Diagnostic Approaches, Therapeutic Management, and Associated Comorbidities of Prurigo Nodularis (Chronic Nodular Prurigo): An Observational Study in Clinical Practice in Spain

International Journal of Dermatology
Prurigo nodularis/chronic nodular prurigo (PN/CNP) is a subtype of chronic prurigo characterized by pruritic nodules on the limbs and trunk. It predominantly affects older adults and women.
J. Armario-Hita, J. Pereyra-Rodríguez, Francisco Javier de Ortiz de Frutos, P. Herranz, J. Silvestre-Salvador, M. Rodríguez Serna, Esther Serra, M. Tribó, J. Carrascosa, Á. Flórez, Juan Antonio Ratón, R. Ruiz-Villaverde   +11 more
semanticscholar   +1 more source