Results 161 to 170 of about 4,117 (197)
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Prurigo Nodularis and Uremia

Southern Medical Journal, 1975
Patients with uremia frequently have generalized pruritus that is usually related to a disturbance of calcium and phosphorus metabolism. This report describes three patients with uremia who had prurigo nodularis due to localized scratching and rubbing. The diagnosis of uremia in one case was made when the patient was hospitalized for evaluation of skin
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Comorbidities in prurigo nodularis

Clinics in Dermatology
Prurigo nodularis (PN) is a chronic inflammatory skin condition characterized by intense pruritus and hyperkeratotic nodules commonly found on the trunk and extremities. The pathogenesis of PN involves neuroimmune dysregulation, mediated by various inflammatory cytokines and neuropeptides. PN significantly impacts patients' quality of life.
Jaya, Manjunath   +3 more
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Prurigo nodularis and the microbiome

Clinics in Dermatology
Prurigo nodularis (PN) is a chronic skin condition that profoundly impacts quality of life. Histopathological studies of itchy hyperkeratotic nodules show dense infiltrates of T lymphocytes, mast cells, and eosinophils. A robust inflammatory response is implicated, coupled with key changes in neuronal plasticity that affect nerve fiber architecture and
Hyun Ji, Lee, Hei Sung, Kim
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Prurigo nodularis of Hyde: an update

Journal of the European Academy of Dermatology and Venereology, 2000
AbstractPrurigo nodularis of Hyde is an unusual disorder of unknown aetiology characterized by extremely pruritic nodules with well defined clinical and histopathological aspects. The literature on this disease is reviewed, focusing on the historical background, aetiology, pathogenesis, histopathology and ultrastructure, clinical aspects, differential ...
L W, Accioly-Filho   +2 more
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Merkel cells and prurigo nodularis

Journal of the American Academy of Dermatology, 1994
Increased numbers of dermal nerves have been demonstrated in prurigo nodularis and have been theoretically linked to the intense pruritus. We hypothesized that the neuronal proliferation in prurigo nodularis might be associated with an increased density of Merkel cells because they are also a component of the neurocutaneous system.We examined skin ...
G T, Nahass, N S, Penneys
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Bullous pemphigoid and prurigo nodularis

Journal of the American Academy of Dermatology, 1986
Bullous pemphigoid is a chronic blistering disorder characterized by specific clinical, histologic, and immunofluorescent findings. Several variants have been described, including pemphigoid nodularis, which may mimic or evolve from or into prurigo nodularis. The casual relationship between prurigo nodularis and bullous pemphigoid is unknown.
R K, Roenigk, M V, Dahl
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Follicular occurrence of prurigo nodularis

Journal of Cutaneous Pathology, 1988
Thirty‐eight biopsies of prurigo lesions (22 large, mature nodules and 16 smaller, intermediately developed nodules) were obtained from 17 patients with idiopathic prurigo nodularis Hyde who had not been bitten by insects, nor had other underlying diseases. Each biopsy was serially sectioned to reveal its histological structure.
H, Miyauchi, M, Uehara
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Alitretinoin for prurigo nodularis

Clinical and Experimental Dermatology, 2020
T, Maqbool, J N, Kraft
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Treatment of prurigo nodularis with pregabalin.

Journal of clinical pharmacy and therapeutics, 2012
Prurigo nodularis (PN) is a chronic skin condition that is difficult to treat. Pregabalin is one of the possible treatments for PN but its safety and efficacy are not well defined. We aimed to assess the efficacy of pregabalin in patients with PN.Thirty patients (10 men, 20 women; mean age 51.6 ± 9.39 years) were treated with pregabalin (75 mg/day) for
Mazza, Marianna   +5 more
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Prurigo nodularis.

The Journal of family practice, 1993
Prurigo nodularis is a chronic skin disorder that is frequently misdiagnosed. It is characterized by multiple pea-sized nodules that develop on the skin, particularly on the anterior leg and thigh. These lesions are intensely pruritic and frequently become excoriated and infected.
P W, Linhardt, A D, Walling
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