Results 1 to 10 of about 123,662 (255)

Interleukin-31 as a Clinical Target for Pruritus Treatment [PDF]

open access: goldFrontiers in Medicine, 2021
In recent years, the published literature has suggested the key involvement of the cytokine interleukin-31 (IL-31) in the symptomatology of pruritus, and both IL-31 and its receptor have become potential therapeutic targets for a range of pruritic ...
Kenji Kabashima, Hiroyuki Irie
openalex   +2 more sources

Development of the pruritus-associated stress scale: a cross-sectional pilot study. [PDF]

open access: yesFront Med (Lausanne)
BackgroundA significant relationship exists between perceived stress and the exacerbation and perpetuation of chronic pruritic dermatoses. Despite this, there is a notable absence of validated tools to specifically measure pruritus-associated stress ...
Royeck S   +11 more
europepmc   +2 more sources

Pruritus as a Distinctive Feature of Type 2 Inflammation

open access: yesVaccines, 2021
Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic. Pruritus might have a tremendous impact on patients’ quality of life and strongly interfere with sleep, social, and work activities.
Simone Garcovich   +2 more
exaly   +2 more sources

Peak Pruritus Numerical Rating Scale: psychometric validation and responder definition for assessing itch in moderate‐to‐severe atopic dermatitis

open access: yesBritish Journal of Dermatology, 2019
Moderate‐to‐severe atopic dermatitis (AD) is a chronic disease characterized by intense, persistent and debilitating itch, resulting in sleep deprivation, signs of anxiety and depression, impaired quality of life and reduced productivity.
Gil Yosipovitch
exaly   +2 more sources

Treatment of Uremic Pruritus: A Systematic Review

open access: yesAmerican Journal of Kidney Diseases, 2017
BACKGROUND Uremic pruritus is a common and burdensome symptom afflicting patients with advanced chronic kidney disease (CKD) and has been declared a priority for CKD research by patients. The optimal treatments for uremic pruritus are not well defined.
Paul Komenda, Blake Lerner, Nicole Askin
exaly   +2 more sources

Pruritus is common in patients with chronic liver disease and is improved by nalfurafine hydrochloride

open access: yesScientific Reports, 2021
Pruritus is known to be a common complication in hepatitis patients, but the exact frequency and degree are not fully elucidated. Thus, we evaluated pruritus of 450 patients with chronic liver disease at our hospital.
Shuhei Yoshikawa   +18 more
doaj   +2 more sources

Metabolomic analysis of uremic pruritus in patients on hemodialysis.

open access: yesPLoS ONE, 2021
Pruritus is a common debilitating symptom experienced by hemodialysis patients. Treatment is difficult because the cause of uremic pruritus is not known. This study addressed the hypothesis that pruritus is caused by solutes that accumulate in the plasma
Christian G Bolanos   +4 more
doaj   +2 more sources

Have We Just Scratched the Surface? A Narrative Review of Uremic Pruritus in 2020

open access: yesCanadian Journal of Kidney Health and Disease, 2020
Purpose of review: Uremic pruritus is a highly prevalent and debilitating symptom in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD).
Claire E. Martin   +3 more
doaj   +2 more sources

Impact of Pruritus on Quality of Life and Current Treatment Patterns in Patients with Primary Biliary Cholangitis

open access: yesDigestive Diseases and Sciences, 2022
Background and Aims Patients with primary biliary cholangitis (PBC) often suffer with pruritus. We describe the impact of pruritus on quality of life and how it is managed in a real-world cohort.
M. Mayo   +51 more
semanticscholar   +1 more source

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