Results 161 to 170 of about 93,014 (296)

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

PRURITUS ANI [PDF]

BMJ, 1931
openaire   +2 more sources

Real‐World Safety and Effectiveness of Glatiramer Acetate in Patients With Multiple Sclerosis: Final Results of Post‐Marketing Surveillance in Japan

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino, Eriko Hayashi, Mai Itani, Jun‐ichi Kira   +3 more
wiley   +1 more source

Uremic Pruritus [PDF]

The International Journal of Artificial Organs, 1996
K, Hiroshige, A, Kuroiwa
openaire   +2 more sources

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

Chronic Pruritic Papular Eruption in an Elderly Man

JEADV Clinical Practice, EarlyView.
Filipe Monteiro, Inês Tribolet‐Abreu, Gustavo Almeida‐Silva, Inês Amaral, Ivânia Soares, Sónia Fernandes, Joana Antunes   +6 more
wiley   +1 more source

Linerixibat reduces cholestatic pruritus in patients with primary biliary cholangitis. [PDF]

Transl Gastroenterol Hepatol
Kanda T, Sasaki-Tanaka R, Kamimura H, Terai S.   +3 more
europepmc   +1 more source

The misspelling of pruritus

Journal of the American Academy of Dermatology, 1989
K F, Helm, L, Goldsmith
openaire   +2 more sources

Effect of Intraoperative Regional Anesthesia on Postoperative Outcomes in Pediatric Cardiac Surgery—A Systematic Review of Randomized Controlled Trials

Pediatric Anesthesia, EarlyView.
ABSTRACT Objective To conduct a meta‐analysis of postoperative outcomes following the use of regional anesthesia in pediatric cardiac surgery. Data Sources We searched PubMed (MEDLINE), Web of Science, CINAHL, CENTRAL, and Scopus in December 2024 (PROSPERO: CRD420025635423; registered January 2025).
Katariina Hiisivuori, Heli Salmi, Vesa K. Kontinen, Ilari Kuitunen   +3 more
wiley   +1 more source

New and emerging treatments for PBC-related pruritus. [PDF]

Drugs Context
Anderson SL.
europepmc   +1 more source