Results 61 to 70 of about 10,558 (183)

AI‐assisted VMAT planning incorporating deep learning‐based dose prediction for head and neck cancer: feasibility of quality standardization and human intervention for irregular cases

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Volumetric‐modulated arc therapy (VMAT) represents a standard of care for head and neck cancer (HNC). However, treatment plan quality depends heavily on the planner's expertise, thereby challenging the standardization of treatment quality.
Seiji Tomori, Kakutaro Narazaki, Shun Tasaka   +2 more
wiley   +1 more source

Pseudorabies virus (PRV)-specific antibodies suppress intracellular viral protein levels in PRV-infected monocytes

Journal of General Virology, 2003
Blood monocytes infected with pseudorabies virus (PRV), a swine alphaherpesvirus, are not eliminated efficiently by antibody-dependent immunity and may occasionally transport PRV to the pregnant uterus of vaccinated animals. This study examines in vitro the long-term fate of PRV-infected monocytes cultivated in the presence of porcine PRV-specific ...
Herman W, Favoreel, Gerlinde R, Van de Walle, Hans J, Nauwynck, Thomas C, Mettenleiter, Maurice B, Pensaert   +4 more
openaire   +2 more sources

Systematic review of physical and dosimetric criteria for managing CIEDs in radiotherapy: A medical physicist's perspective

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Aim Current radiotherapy (RT) guidelines for Cardiac Implantable Electronic Devices (CIEDs) are largely based on clinical management strategies and retrospective reports. This systematic review adopts a medical physics perspective to provide a critical, quantitative analysis of the technical evidence required for developing robust safety ...
Tiziana Malatesta, Agnese Barbareschi, Rita Alaimo, Emilio Mezzenga, Maria Grazia Brambilla, Anna Delana, Stefano Andreoli, Rita Consorti, Stefano Ren Kaiser, Marco Mapelli, Eugenia Moretti, Maria Mormile, Giulia Rambaldi Guidasci, Mara Severgnini, Lidia Strigari, Maria Daniela Falco   +15 more
wiley   +1 more source

Automatic Distribution of PRVs for Leakage Reduction

The 3rd International Joint Conference on Water Distribution Systems Analysis & Computing and Control for the Water Industry (WDSA/CCWI 2024)
In this work, an automatic distribution of the pressure reduction valves (PRVs) is proposed. First, a well-calibrated hydraulic model is required. The model of Manresa, a city of Catalunya in the Mediterranean area, was calibrated using pressure sensors, and the background leakage was estimated using weighted emitter coefficients.
Pérez Magrané, Ramon, Roca Puntí, Guillem, Grau Torrent, Sergi   +2 more
openaire   +2 more sources

Construction of Two Recombinant Pseudorabies Viruses with Deletion of Virulence Genes and Evaluation of Their Immune Protection in Mice and Piglets

Vaccines
Background: Since 2011, re-emerging pseudorabies virus (PRV) variant strains have been widespread in swine herds immunized with the classical PRV vaccine in China, suggesting that it is necessary to develop a new vaccine against these PRV variant strains.
Shanghui Wang, Longfei Han, Jimin Yu, Guangqiang Ye, Hongyang Liu, Yunfei Liu, Qiongqiong Zhou, Zhaoxia Zhang, Changjiang Weng   +8 more
doaj   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, Volume 13, Issue 45, 13 August 2026.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection Against Pseudorabies Virus

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Engagement of understudied populations as community change: The South Texas ADRC model

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Many populations experiencing the highest burdens of Alzheimer's disease and related dementias remain understudied, in part because traditional recruitment and retention models are insufficient to support sustained engagement. The Outreach, Recruitment, and Engagement Core (OREC) of the South Texas Alzheimer's Disease Research Center ...
Gladys E. Maestre, Neela K. Patel, Rosa V. Pirela, Robin C Hilsabeck, Kendra Stine, Fayron R. Epps, Neyra Garcia, Stephanie Santiago‐Mejias, Roberto Reyes, Claudia L. Satizabal, Silvia Mejia‐Arango, A. Campbell Sullivan, Omar Oropeza, Monica Gireud‐Goss, Hector Rodriguez, Hector Trevino, Andrea Ramirez, Vanessa M. Young, Ney Alliey‐Rodriguez, Ashley LaRoche, Carlos J. Martinez‐Menendez, Jeremy A. Tanner, Leah Otto, Cynthia De La Garza‐Parker, Noe Garza, Melissa Flores, Norene Casas, Sylvia Robles, Angelica Davila, Cristian A. Maestre, Eric Shipp, Jesus D. Melgarejo, Gabriel A. de Erausquin, Sarah Williams‐Blangero, Sudha Seshadri   +34 more
wiley   +1 more source

Eigencones and the PRV conjecture

, 2009
Let $G$ be a complex semisimple simply connected algebraic group. Given two irreducible representations $V_1$ and $V_2$ of $G$, we are interested in some components of $V_1\otimes V_2$. Consider two geometric realizations of $V_1$ and $V_2$ using the Borel-Weil-Bott theorem.
openaire   +2 more sources

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2764-2776, August 2026.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source