Results 151 to 160 of about 112,336 (261)

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Correction: Biochemical failure after radical prostatectomy with PSA ≤ 1 ng/mL: prediction of PSMA-positive metastatic disease. [PDF]

Ann Nucl Med
Santo G, Rosarno H, Restuccia A, Cascini GL, Grillone F, Cicone F.   +5 more
europepmc   +1 more source

Revisiting EWMA in High‐Frequency‐Based Portfolio Optimization: A Comparative Assessment

Journal of Applied Econometrics, EarlyView.
ABSTRACT This paper compares the statistical and economic performance of state‐of‐the‐art high‐frequency (HF) based multivariate volatility models with a simpler, widely used alternative, the Exponentially Weighted Moving Average (EWMA) filter. Using over two decades of 100 U.S.
Laura Capera Romero, Anne Opschoor
wiley   +1 more source

Cardiovascular Risk in Psoriatic Arthritis: Mechanisms, Risk Assessment, and Long-Term Management Implications. [PDF]

Int J Mol Sci
Totolici S, Vrabie AM, Buzea CA, Badila E.   +3 more
europepmc   +1 more source

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Diagnosis of Prostate Cancer: A Comparative Evaluation of Biological Techniques. [PDF]

Diseases
Tshoni UA, Mbonane TP, Rathebe PC.
europepmc   +1 more source

Synthesis of polyaniline/TiO2 nanocomposites: effects of acid and aniline concentrations on material properties and photocatalytic performance for sulfamethoxazole degradation

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This work investigated the synthesis of TiO2‐P25/polyaniline (PANI) nanocomposites, denoted as PANI– TiO2, via chemical oxidative polymerization under different aniline:H+ molar ratios, and evaluated their performance in heterogeneous photocatalysis (HP).
Vanessa Mendonça Mendes Vargas, Susan Leonora Antunes, Carla Dalmolin, Sérgio Henrique Pezzin   +3 more
wiley   +1 more source

Normalized periprostatic adipose tissue thickness: an imaging marker associated with prostate biopsy outcomes among patients with PI-RADS and PSA double gray zone. [PDF]

Adipocyte
Xiong T, Shen L, Fan Y, Liu Z, Jin S, Wu H, Yang Z, Niu Y.   +7 more
europepmc   +1 more source

Optimal Selection of the Effective Echo Time (TEeff) for T2‐Weighted Fast‐Spin‐Echo MRI of the Prostate at 3.0 T: Effect on Lesion Conspicuity

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Clinical T2‐weighted (T2W) MRI of prostate cancer (PCa) usually implements a 2D fast‐spin‐echo (FSE) sequence, but understanding the echo‐time‐dependent contrast behavior is not straightforward due to the complicated FSE signal evolution.
Dahan Kim, Ronard Pabi, Eric A. Borisch, Adam T. Froemming, Roger C. Grimm, Sara Hassanzadeh, Akira Kawashima, Ayumu Kido, Naoki Takahashi, John V. Thomas, Stephen J. Riederer   +10 more
wiley   +1 more source

New biosensor for the early detection of tPSA in the serum of prostate cancer patients using a Tb-anthracene-9-carboxaldehyde complex embedded in a modified cellulose polymer thin film. [PDF]

RSC Adv
Abo Gabal MT, El-Desouky MA, Hanna DH, Attia MS.   +3 more
europepmc   +1 more source