Results 221 to 230 of about 191,930 (288)

Bipolar Androgen Therapy as a Potential Mechanistic Bridge to Enhance PARP Inhibitor Efficacy in Prostate Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Prostate cancer remains a leading cause of cancer‐related mortality, largely driven by progression to metastatic castration‐resistant prostate cancer (mCRPC). Although poly(ADP‐ribose) polymerase inhibitors (PARPis) have improved outcomes in patients with homologous recombination repair (HRR) alterations, particularly in BRCA2‐mutated disease,
Jhen‐Hao Jhan   +4 more
wiley   +1 more source

Correction: Comparative proteome and serum analysis identified FSCN1 as a marker of abiraterone resistance in castration-resistant prostate cancer. [PDF]

open access: yesProstate Cancer Prostatic Dis
Csizmarik A   +16 more
europepmc   +1 more source

Tibia‐first, gap‐balanced patient‐specific alignment in total knee arthroplasty achieves better ligament balance than mechanical, kinematic and functional alignment strategies

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study evaluates four different alignment techniques to assess total knee arthroplasty (TKA) balance. Methods A prospective cohort of 400 patients undergoing primary robotic‐assisted cruciate‐retaining TKA was analysed. The Velys TKA robotic system collects a balance curve that enables the surgeon to intraoperatively analyse the ...
Guido Wierer, Mark Clatworthy
wiley   +1 more source

Mixed Litter Decomposition Drives Functional Gene Rearrangement in the Microbial Carbon Cycle

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Understanding how mixed‐species litter decomposition regulates microbial communities and carbon cycling is vital for guiding ecosystem restoration and climate change mitigation, as it is a key process for nutrient cycling and carbon sequestration. A 15‐month field experiment compared single‐species (Pinus sylvestris var.
Jiaying Liu   +6 more
wiley   +1 more source

Association of Early-Life Exposures With Later Diagnosis of Spondyloarthritis: A Population-Based Case-Control Study. [PDF]

open access: yesJ Rheumatol
Altaffer AL   +5 more
europepmc   +1 more source

Artificial Voices, Real Causes: The Dilemma of Virtual Influencer‐Driven Brand Activism

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT Brands are more frequently adopting virtual influencers (VIs) to lead activism campaigns. However, little is known about when and how such activism effectively drives consumer engagement. This research, in Study 1, examines 14,464 Instagram posts from 18 diverse VIs using large‐scale analytics to assess engagement intensity and the dynamics of
Sampa Anupurba Pahi   +4 more
wiley   +1 more source

Dynamic Predictions and Predictimands for Salvage Therapy in Recurrent Prostate Cancer Using Joint Models. [PDF]

open access: yesStat Med
Owens L   +8 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

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