Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley +1 more source
A Study on Early Screening and Disease Characteristics of Psoriatic Arthritis Based on PEST Questionnaire and Musculoskeletal Ultrasound. [PDF]
Wei J +8 more
europepmc +1 more source
Feedback is the most powerful driver of learning, but it can afford variable effects depending on the method used. The design of feedback for computer‐based assessment—now increasingly prevalent in higher education—remains relatively underexplored, particularly for pharmacology education.
Claire Y. Hepburn
wiley +1 more source
Development of Arthritis in a Large Real-World Cohort of Patients With Pediatric Onset Psoriasis. [PDF]
Al-Gawahiri M +5 more
europepmc +1 more source
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić +4 more
wiley +1 more source
Biologics and the psoriatic march: Is it time to rethink early intervention? [PDF]
Gisondi P.
europepmc +1 more source
Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim +5 more
wiley +1 more source
Clinical and anatomical characteristics of craniocervical junction arteriovenous fistulas fed from the vertebral artery dural ring: patient series. [PDF]
Uchikado H +6 more
europepmc +1 more source
ABSTRACT This is a retrospective case study of an antisemitic lone actor terrorist who completed the deadliest attack against the Jewish community in American history. The analysis through the lens of the Terrorist Radicalization Assessment Protocol (TRAP‐18) finds that 72% of the warning indicators were present, including four proximal warning ...
Molly Amman, Julia Kupper, J. Reid Meloy
wiley +1 more source
Diagnosis and therapeutic management of psoriatic arthritis: summary of 2024 update of the Spanish clinical practice guideline (ESPOGUIA). [PDF]
Ramírez J +11 more
europepmc +1 more source

