Results 31 to 40 of about 231,085 (342)
Brazilian Journal of Radiation Sciences, 2021 Industrial facilities systems deteriorate over time, thus increasing the possibility of accidents. Risk-Based Inspection (RBI) classifies such systems by their risk information with the purpose of prioritizing inspection efforts.
Raíssa Oliveira Marques +5 more
doaj +1 more source
Cancers, 2019 Prostate Specific Antigen (PSA) fails to discriminate between benign prostatic hyperplasia (BPH) and Prostate Cancer (PCa), resulting in large numbers of unnecessary biopsies and missed cancer diagnoses.
M. Logozzi +12 more
semanticscholar +1 more source
Prostate cancer screening with prostate-specific antigen (PSA) test: a clinical practice guideline
British medical journal, 2018 ### What you need to know What is the role of prostate-specific antigen (PSA) screening in prostate cancer? An expert panel produced these recommendations based on a linked systematic review.1 The review was triggered by a large scale, cluster ...
K. Tikkinen +18 more
semanticscholar +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Desenvolvimento e Meio Ambiente, 2019 Brazilian’s conservation strategies are not limited only by the creation of Protected Areas, either Integral Protection or Sustainable Use. There are distinct strategies that aim to value services provided by ecosystems, combining conservation to the ...
Mário Muniz Tagliari +2 more
doaj +1 more source
Khyber Medical University Journal, 2022 OBJECTIVE: To determine cut-off values for prostate specific antigen density (PSAD) in diagnosing prostate carcinoma in symptomatic patients. METHODS: This cross sectional, observational study conducted at Department of Chemical Pathology and ...
Zujaja Hina Haroon +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Evaluation of serum PSA levels as a biomarker for breast carcinoma in north Indian females
Asian Journal of Medical Sciences, 2014 Objective: Breast cancer has emerged as the most common malignancy among females during the last few years. Early diagnosis is essential for disease management so research is underway to identify potential serological bio markers with acceptable ...
Nikhil Gupta
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source