Results 131 to 140 of about 232,710 (307)

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

Trends in publicly subsidized and private access to GLP‐1 medicines indicated for type 2 diabetes in Australia, 2020–2025

British Journal of Clinical Pharmacology, EarlyView.
Aims GLP‐1 medicines provide substantial cardio‐renal benefits for type 2 diabetes (T2D) and are increasingly used for weight loss. Most high‐income countries subsidize access for T2D with restrictions; use outside of these restrictions occurs through private prescriptions. Despite strong consumer demand, the extent of private access to GLP‐1 medicines
Michael O. Falster, Juliana de Oliveira Costa, Tamara Y. Milder, Joanne Carson, Cade Shadbolt, Brendon L. Neuen, Clare Arnott, Andrew Wilson, Min Jun, Nicole Pratt, Sallie‐Anne Pearson   +10 more
wiley   +1 more source

Twenty years of inhaler therapy: A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to map nationwide trends and prescribing patterns in inhaler use from 2004 to 2023. In light of evolving clinical guidelines and attention to the environmental impact of inhalers within recent years, we also examined variation in prescribing behaviour and patient‐level treatment choices. Methods Using nationwide health registries,
Katrine Bitsch Johansen, Lars Christian Lund, Zandra Nymand Ennis, Andrew Scourfield, Anders Løkke, Sidsel Arnspang Pedersen   +5 more
wiley   +1 more source

Arrhythmic risk stratification in psoriatic arthritis: a retrospective, electrogram-based comparative analysis. [PDF]

RMD Open
Sewerin P, Bismpos D, Lange PS, Horstmann N, Sprave H, Ukena C, Baraliakos X.   +6 more
europepmc   +1 more source

Reply

Arthritis &Rheumatology, EarlyView.
Joseph F. Merola, Cynthia E. Kartman, Peter Fischer, Luna Sun, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +6 more
wiley   +1 more source

Characterizing Low Falling Number in the Absence of Elevated Alpha‐Amylase Activity in Soft White Wheat and the Impact on Japanese Sponge Cakes

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Non‐alpha‐amylase induced low falling number was identified in 2024 soft white wheat. The objectives of this work were to characterize these low falling number samples and determine the impact on end‐product quality. The results were analyzed to determine differences in flour characteristics that might result in a low
Gabriely M. Soncin Alfaro, Alecia M. Kiszonas, Sean M. Finnie, Xiaorong Wu, Jayne Bock, Andrew S. Ross, Amber L. Hauvermale, Alison L. Thompson   +7 more
wiley   +1 more source

Long-term Outcomes in Men with Stable PSA During 5-α Reductase Inhibitor Therapy After Negative Prostate Biopsy: Population-based Study. [PDF]

Eur Urol Open Sci
Ventimiglia E, Westerberg M, Orasson AW, Ahlberg M, Robinson D, Gedeborg R, Stattin P, Garmo H.   +7 more
europepmc   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Behavioral Changes in Children Are Uncommon 4 Weeks After Procedural Sedation and Analgesia With Intranasal Dexmedetomidine and Nitrous Oxide. [PDF]

Paediatr Neonatal Pain
Nikula A, Ryd-Rinder M, Lundeberg S, Lääperi M, Castrén M, Kurland L.   +5 more
europepmc   +1 more source

Internal Carbon Cycles in the Steel Industry: Pathways for CO2 Management and Carbon Capture Utilization

Chemie Ingenieur Technik, EarlyView.
The steel industry accounts for about 7%‐9% of global CO2 emissions. While H2‐based direct reduction is a long‐term route, near‐term solutions are needed for existing plants. Internal carbon cycles reuse steelworks off‐gases and by‐products, enabling circular carbon use and supporting CCU integration.
Florian Haakmann, Nina Kolbe, Julian Suer, Cássia Castro Müller, Nils Jäger   +4 more
wiley   +1 more source