Results 91 to 100 of about 12,314 (276)

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Flexible Pseudo-Relevance Feedback for NTCIR-2

open access: yes, 2008
The University of Cambridge/Microsoft/Toshiba team participated in the NTCIR-2 Japanese-English Cross-Language IR task only, using the Okapi Basic Search System at the University of Cambridge.
Tetsuya Stephen   +2 more
core  

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

open access: yesAdvanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang   +10 more
wiley   +1 more source

Why web-based pseudo relevance feedback systems fail

open access: yes, 2012
 We review pseudo-relevance feedback as a mechanism for expanding short texts. Where short texts exhibit evolving concepts, topics and other characteristics, Web-based feedback systems were touted as the most ideal way of enriching the feature space of ...
J Zhang (7490018)   +2 more
core  

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

open access: yesAdvanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang   +11 more
wiley   +1 more source

Relevance Transformer: Generating Concise Code Snippets with Relevance Feedback

open access: yes, 2020
Tools capable of automatic code generation have the potential to augment programmer's capabilities. While straightforward code retrieval is incorporated into many IDEs, an emerging area is explicit code generation. Code generation is currently approached
Rossetto, Federico   +5 more
core   +1 more source

A Review of Failure Modes and Safety Strategies of Lithium‐Ion Batteries from Materials to Systems

open access: yesAdvanced Science, EarlyView.
A cascade‐aware framework is presented for lithium‐ion battery safety, linking thermal runaway initiation, acceleration, runaway reaction, and propagation with material‐, cell/pack‐, and system‐level interventions. By integrating failure mechanisms, quantitative safety indicators, and staged interception strategies, this review highlights how safer ...
Jin Hyeok Yang   +8 more
wiley   +1 more source

Flexible Pseudo-Relevance Feedback via Direct Mapping and Categorization

open access: yes, 2001
This paper explores various strategies for enhancing the reliability of pseudo-relevance feedback using TREC and NTCIR test collections. For each test request, the number of pseudo-relevanct documents (Ê) or the number of expansion terms (Ì) is ...
Stephen Walker   +2 more
core  

Femtosecond‐Laser Nanocavitation Regenerates SERS‐Active Plasmonic Nanogaps for Longitudinal Molecular Sensing at Biointerfaces

open access: yesAdvanced Science, EarlyView.
A regenerative molecular sensing platform that co‐localizes surface‐enhanced Raman spectroscopy (SERS) sensing and nanocavitation‐based actuation. Femtosecond‐laser triggered nanocavitation produces thermomechanical forces to locally regenerate SERS‐active nanogaps in protein‐rich biofluids while preserving optical performance.
Aditya Garg   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy