Results 111 to 120 of about 302,038 (240)

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer   +11 more
wiley   +1 more source

Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in Pseudomonas aeruginosa

open access: green, 2021
Johanna Ude   +10 more
openalex   +2 more sources

Biosurfactants are involved in the biological control of Verticillium microsclerotia by Pseudomonas spp [PDF]

open access: yes, 2007
DE BACKER, G   +5 more
core   +2 more sources

Resistome flow in global landfill systems

open access: yesiMetaOmics, EarlyView.
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong   +12 more
wiley   +1 more source

Broad‐Spectrum Antimicrobial and Biofilm‐Disrupting Activity of D7: A Novel Disinfectant Effective Against Pseudomonas aeruginosa and Other Clinically Relevant Pathogens

open access: yesiNew Medicine, EarlyView.
ABSTRACT Biofilm‐associated contamination and the presence of multiple pathogenic species on environmental and medical surfaces pose a major challenge in healthcare and hygiene management, contributing significantly to hospital‐acquired infections (HAIs).
Shanghui Gao   +6 more
wiley   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

open access: yesInterdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan   +2 more
wiley   +1 more source

Advances and challenges in point‐of‐care testing for pathogenic bacteria in battlefield injuries

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores trauma‐associated bacterial species, summarizes these biosensor advancements, addresses fabrication challenges, outlines future directions, and aims to guide POCT biosensor development for combat/trauma care bacterial detection.
Junjie Fan   +11 more
wiley   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

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