Results 151 to 160 of about 734,075 (399)

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Silver(I) pyridinyl complexes with benzothiazole, thiophene, and furan moieties: DNA/protein‐binding, antibacterial, antioxidant, and anticancer studies

Archiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Nine Ag(I) complexes of Schiff bases containing thiophene, furan, and pyridine moieties were synthesized and tested for their in vitro antibacterial, antioxidant, and anticancer activities and DNA/bovine serum albumin binding. The nine Ag(I) complexes bound to calf thymus‐DNA by an intercalative binding mode, with the complex bearing a benzothiazole ...
Adesola A. Adeleke, Md. Shahidul Islam, Bernard Omondi   +2 more
wiley   +1 more source

Decreased Sphingosine Due to Down-Regulation of Acid Ceramidase Expression in Airway of Bronchiectasis Patients: A Potential Contributor to Pseudomonas aeruginosa Infection

Infection and Drug Resistance, 2023
Qian Qi,1,2,* Jiawei Xu,1,2,* Yujiao Wang,3,* Jian Zhang,1 Mingxia Gao,1 Yu Li,4 Liang Dong1,2 1Department of Respiratory, the First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong ...
Qi Q, Xu J, Wang Y, Zhang J, Gao M, Li Y, Dong L   +6 more
doaj  

Relation between Insertion Sequences and Genome Rearrangements in Pseudomonas aeruginosa [PDF]

arXiv, 2017
During evolution of microorganisms genomes underwork have different changes in their lengths, gene orders, and gene contents. Investigating these structural rearrangements helps to understand how genomes have been modified over time. Some elements that play an important role in genome rearrangements are called insertion sequences (ISs), they are the ...
arxiv  

Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis

Clinical Microbiology Reviews, 2018
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF).
M. Parkins, R. Somayaji, V. Waters
semanticscholar   +1 more source

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

Advanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Liping Zeng, Guoxin Zhang, Lu Zhou, Hongkai Bi, Liang Zhang   +9 more
wiley   +1 more source

Susceptibility pattern of multi-drug resistance Pseudomonas aeruginosa isolates from tertiary care hospital in Riyadh, KSA

Journal of King Saud University: Science, 2023
Objectives: Pseudomonas aeruginosa is important pathogens commonly cause nosocomial infections. The occurrence of multi-resistant organisms (MROs) of Pseudomonas aeruginosa strains have been increased worldwide and limiting the therapeutic options.
Hanan O. Alshammari, Ali Somily, Malak Yahia Qattan, Roua A. Alsubki, Ihab M. Moussa   +4 more
doaj  

Evaluation of prevalence and antibiogram of multi drug resistant, extensively drug resistant and pan drug resistant Pseudomonas aeruginosa in patients visiting a tertiary care hospital in central India

CHRISMED Journal of Health and Research, 2014
Introduction: Antibiotic resistance is an increasing concern worldwide, specially in Gram negative bacilli where there is a paucity of new and effective antimicrobial agents.
Gunjan Shrivastava, G S Bhatambare, K B Patel   +2 more
doaj   +1 more source

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients

European Respiratory Journal, 2018
Pseudomonas aeruginosa is a challenging bacterium to treat due to its intrinsic resistance to the antibiotics used most frequently in patients with community-acquired pneumonia (CAP).
M. Restrepo, B. L. Babu, L. Reyes, J. Chalmers, N. Soni, O. Sibila, P. Faverio, C. Cillóniz, W. Rodriguez-Cintron, S. Aliberti   +9 more
semanticscholar   +1 more source

The multifactorial resistance of Pseudomonas aeruginosa

EXCLI journal, 2020
EXCLI Journal;Vol. 19. 2020, pp.
openaire   +3 more sources