Results 71 to 80 of about 5,165 (174)

Bioimaging With Fluorescent Nucleic‐Acid Aptamers for the Specific Detection and Quantification of Pseudomonas aeruginosa Alone and in Heterogeneous Bacterial Populations

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Aptamers are promising candidates for diagnostic applications due to their broad pathogen detection capability. The open‐access quantitative bioimaging software we have developed for confocal images has validated aptamer F23 as a promising tool to distinguish Pseudomonas aeruginosa from different bacterial strains. ABSTRACT Aptamers, short nucleic acid
Chaimae Mezouarhi, Romain Vauchelles, Basma Abdallah, Régine Janel, Mouna Ouadghiri, Hassan Ait Benhassou, Sandrine Pelet, Pierre Fechter, Laurence Choulier   +8 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen

Journal of Fasa University of Medical Sciences, 2015
Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi, Aziz Japoni, Manouchehr Rasouli, Salimeh Ebrahimnezhad   +3 more
doaj  

Impacts of some plant extracts and how effectively they work against Pseudomonas aeruginosa: Review article

Biobacta Journal of Biochemistry and Molecular Biology
One way that pathogens develop resistance to pharmaceuticals is by forming biofilms, which are 3-D communities of bacteria. As a result, there is considerable interest in identifying new antibiofilm agents from nature that can be used to treat these ...
Assala Jawad, Ghinwa Majid, Zina Al-Obaidi   +2 more
doaj   +1 more source

Structural Insights into Pseudomonas aeruginosa Exotoxin A-Elongation Factor 2 Interactions: A Molecular Dynamics Study. [PDF]

J Chem Inf Model, 2023
Gholami A, Minai-Tehrani D, Mahdizadeh SJ, Saenz-Mendez P, Eriksson LA.   +4 more
europepmc   +1 more source

Pseudomonas aeruginosa exotoxin A and keratitis in mice.

Investigative ophthalmology & visual science, 2002
To determine the importance of Pseudomonas aeruginosa exotoxin A (ETA) as a virulence factor in corneal disease.Isogenic mutants deficient in ETA were constructed in P. aeruginosa strains PAO1 and ATCC 19660 by allelic exchange and then evaluated for virulence in a mouse model of bacterial keratitis.
Christopher M, Pillar, Jeffery A, Hobden
openaire   +1 more source

Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.

PLoS ONE, 2012
Homologs of the transcriptional regulator PtxS are omnipresent in Pseudomonas, whereas PtxR homologues are exclusively found in human pathogenic Pseudomonas species.
Abdelali Daddaoua, Sandy Fillet, Matilde Fernández, Zulema Udaondo, Tino Krell, Juan L Ramos   +5 more
doaj   +1 more source

Effect of Satureja khuzistanica essential oil (SKEO) extract on expression of lasA and lasB genes in Pseudomonas aeruginosa

Iranian Journal of Microbiology, 2019
Background and Objectives: Expressions of lasA and lasB genes of Pseudomonas aeruginosa are associated with bacterium pathogenicity. The present study was aimed to assess the effect of Satureja khuzistanica essential oil (SKEO) extract on expression of ...
Davoud Iman Islamieh, Davoud Afshar, Davoud Esmaeili   +2 more
doaj   +1 more source

Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of Pseudomonas aeruginosa Exotoxin A. [PDF]

Pharmaceutics, 2021
Li R, Laurent F, Taverner A, Mackay J, De Bank PA, Mrsny RJ.   +5 more
europepmc   +1 more source

DEVELOPMENT OF THE VACCINE BASED ON THE RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. The aim is obtaining, investigation and selection of recombinant antigens for inclusion theirs into the against Pseudomonas vaccine. Materials and methods. The genes encoding of the outer  membrane proteins F, L and I and Exotoxin A were synthesized
N. A. Mihailova, E. M. Zimina, A. V. Soldatenkova, A. A. Kaloshin   +3 more
doaj   +1 more source