Results 161 to 170 of about 14,191 (208)

Landscape of resistance to ceftolozane/tazobactam and ceftazidime/avibactam in strains of Pseudomonas aeruginosa: a genomic approach in strains without selection pressure in a tertiary-care paediatric hospital in Mexico. [PDF]

open access: yesBMC Infect Dis
A Méndez HE   +8 more
europepmc   +1 more source

Characterization of Exotoxin of Pseudomonas aeruginosa

Journal of Infectious Diseases, 1974
Abstract : Heat-labile exotoxin of Pseudomonas aeruginosa has been purified and concentrated. Studies in mice have shown that the toxin affects protein synthesis in the liver within 3 hr of administration, whereas inhibition of protein synthesis in other organs occurs only during terminal stages.
O R, Pavlovskis   +2 more
openaire   +2 more sources

Pseudomonas exotoxin — Immunotoxins

1988
Monoclonal antibodies can be coupled with PE to make very potent ITs. Two of these ITs (PE-HB21 and OVB-3-PE) have been shown to have antitumor activity in a nude mouse model of ovarian cancer. PE ITs are at least 10-fold more active than the corresponding RTA IT.
D J, FitzGerald   +2 more
openaire   +2 more sources

Pseudomonas aeruginosa Exotoxin A

Journal of Burn Care & Rehabilitation, 1992
Bacterial concentrations greater than 10(5) colony-forming units/gm of tissue prevent wound healing. However, it has not been determined whether it is the number of bacteria or a toxin produced by these organisms that impedes the wound healing process.
John P. Heggers   +4 more
openaire   +1 more source

Exotoxins of Pseudomonas aeruginosa. II. Concentration, Purification, and Characterization of Exotoxin A

Journal of Infectious Diseases, 1973
Exotoxin A of Pseudomonas aeruginosa (PA-103) could be concentrated readily by precipitation with zinc acetate and ammonium sulfate. The toxin was purified by column chromatography with use of DEAE-cellulose and Sephadex G-200. The final product contained about 8,000 mouse LD,,0/mg of protein.
P V, Liu, S, Yoshii, H, Hsieh
openaire   +2 more sources

Crystallization of exotoxin A from Pseudomonas aeruginosa

Journal of Molecular Biology, 1982
Abstract Exotoxin A from Pseudomonas aeruginosa has been crystallized in a form suitable for high resolution diffraction analysis. The crystals, grown in the presence of high concentrations of polyethylene glycol (20%, w/v) and of NaCl (1.5 m ), are monoclinic and contain one monomeric toxin molecule per asymmetric unit. The space group is P 2 1 ,
R J, Collier, D B, McKay
openaire   +2 more sources

Pseudomonas aeruginosaExotoxin A

New England Journal of Medicine, 1980
Pseudomonas aeruginosa is an opportunistic pathogen that causes more than 100,000 infections in the United States each year. Pseudomonas infections are associated with considerable morbidity and mortality despite the use of modern antibiotics.1 Recognition of the limitations of existing therapy for pseudomonas disease has stimulated renewed interest in
openaire   +2 more sources

The production of convulsions by an exotoxin from Pseudomonas tabaci

Toxicology and Applied Pharmacology, 1969
Abstract The phytopathogenic bacterium, Pseudomonas tabaci , produces, in culture, an exotoxin which, when purified, causes seizures in mice and rats. The syndrome is similar to that produced by methionine sulfoximine (L-MSO). However, the toxin is at least 10-fold or more potent than is L-MSO.
C, Lamar   +3 more
openaire   +2 more sources

Pseudomonas aeruginosa Exotoxin: Effect on Cell Cultures

Journal of Infectious Diseases, 1972
Abstract : An exotoxin, toxic to both mice and cultured cells, was isolated from cultures of Pseudomonas aeruginosa. Relatively small amounts of the exotoxin inhibited the uptake of uridine and amino acids by Vero cells. Within limits, this toxic action was reversible and could be inactivated by heating at 70 C or by proteolytic digestion, but it was ...
O R, Pavlovskis, F B, Gordon
openaire   +2 more sources

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