Results 91 to 100 of about 317,943 (300)

Using honey to heal diabetic foot ulcers [PDF]

, 2008
Diabetic ulcers seem to be arrested in the inflammatory/proliferative stage of the healing process, allowing infection and inflammation to preclude healing.
Aaltonen, LA, Ballereau, S, Barclay, E, Broderick, P, Campbell, H, Carvajal-Carmona, LG, Casey, G, Cazier, JB, Chander, I, Cheadle, JP, Conti, D, Deary, I, Dobbins, SE, Domingo, E, Duggan, DJ, Dunlop, MG, Easton, D, Farrington, SM, Frampton, M, Gallinger, S, Gorman, M, Grimes, G, Henrion, M, Hopper, J, Houlston, RS, Jenkins, MA, Jones, AM, Kerr, DJ, Kirac, I, Kovacević, D, Lindblom, A, Liu, T, Lloyd, A, Lubbe, S, Ma, YP, Martin, L, Matsuda, K, Mecklin, JP, Midgley, R, Nakamura, Y, Newcomb, P, Okada, Y, Olver, B, Ooi, LY, Palles, C, Penegar, S, Pharoah, P, Prendergast, J, Renkonen-Sinisalo, L, Rudan, I, Schumacher, F, Semple, C, Shah, M, Smillie, C, Smith, CG, Spain, S, Starr, JM, Tenesa, A, Theodoratou, E, Tomlinson, IP, Vijayakrishnan, J, West, H, Whiffin, N, Zgaga, L   +63 more
core   +2 more sources

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Bacterial Biofilm and its Clinical Implications [PDF]

, 2018
Microbial biofilm created huge burden in treatment of both community and hospital infections. A biofilm is complex communities of bacteria attached to a surface or interface enclosed in an exopolysaccharide matrix and protected from unfavorable ...
Shakibaie, Prof
core  

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

Advanced Science, EarlyView.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding, Mengying Wang, Xiaoqing Xu, Dou Wang, Xi Chen, Shuxian Li, Xiawan Zheng, You Che, Yu Deng, Tommy T. Y. Lam, Liguan Li, Tong Zhang   +11 more
wiley   +1 more source

Pseudomonas aeruginosa: An Uncommon Cause of Antibiotic-Associated Diarrhea in an Immunocompetent Ambulatory Adult

Case Reports in Gastrointestinal Medicine, 2020
Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen known to cause enterocolitis in children, amongst other types of infections. Pseudomonas aeruginosa has been widely reported as a cause of antibiotic-associated diarrhea in adult ...
Ryan T. Hoff, Ami Patel, Alan Shapiro
doaj   +1 more source

Effects of propidium monoazide (PMA) treatment on mycobiome and bacteriome analysis of cystic fibrosis airways during exacerbation [PDF]

, 2016
Introduction and Purpose : Propidium monoazide (PMA)-pretreatment has increasingly been applied to remove the bias from dead or damaged cell artefacts, which could impact the microbiota analysis by high-throughput sequencing. Our study aimed to determine
Audebert, Christophe, Delhaes, Laurence, Deschaght, Pieter, Loywick, Alexandre, Merlin, Sophie, Nguyen, Linh Do Ngoc, Van daele, Sabine, Vaneechoutte, Mario, Viscogliosi, Eric   +8 more
core   +3 more sources

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Use of the Anti-Pseudomonas Vaccine for Prophylaxis and Treatment of Nosocomial Infections in Patients with Severe Burn Trauma [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2015
Objective. To explore potential of anti-Pseudomonas vaccine for the prophylaxis and treatment of infections caused by Pseudomonas aeruginosa in patients with severe burn trauma. Materials and Methods.
Bagin V.A., Trofimova Yu.Yu., Rudnov V.A., Golubkova A.A., Savitzkiy A.A., Korobko I.A., Wein V.I.   +6 more
doaj  

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source