Immune Responses to Pseudomonas aeruginosa Biofilm Infections
Frontiers in Immunology, 2021 Pseudomonas aeruginosa is a key pathogen of chronic infections in the lungs of cystic fibrosis patients and in patients suffering from chronic wounds of diverse etiology. In these infections the bacteria congregate in biofilms and cannot be eradicated by
Claus Moser +8 more
doaj +2 more sources
Epidemiology and risk factors of extensively drug-resistant Pseudomonas aeruginosa infections. [PDF]
PLoS ONE, 2018 The incidence of nosocomial infections from extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) has been increasing worldwide. We investigated the prevalence and factors associated with XDR-PA infections, including the factors that predict ...
Nattawan Palavutitotai +4 more
doaj +2 more sources
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections. [PDF]
Sci Rep, 2016 Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Danis-Wlodarczyk K +13 more
europepmc +2 more sources
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics
Cells, 2023 Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which causes many severe acute and chronic infections with high morbidity, and mortality rates as high as 40%. What makes P. aeruginosa a particularly challenging pathogen is its
Stephen J Wood, T. Kuzel, S. Shafikhani
semanticscholar +1 more source
The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update
Drugs, 2021 Pseudomonas aeruginosa is a Gram-negative bacterial pathogen that is a common cause of nosocomial infections, particularly pneumonia, infection in immunocompromised hosts, and in those with structural lung disease such as cystic fibrosis. Epidemiological
D. Reynolds, M. Kollef
semanticscholar +1 more source
Pseudomonas aeruginosa Infections in Cancer Patients
Pathogens, 2022 Pseudomonas aeruginosa (P. aeruginosa) is one of the most frequent opportunistic microorganisms causing infections in oncological patients, especially those with neutropenia.
Paulina Paprocka +5 more
semanticscholar +1 more source
Clinical Impact of Antibiotics for the Treatment of Pseudomonas aeruginosa Biofilm Infections
Frontiers in Microbiology, 2020 Bacterial biofilms are highly recalcitrant to antibiotic therapies due to multiple tolerance mechanisms. The involvement of Pseudomonas aeruginosa in a wide range of biofilm-related infections often leads to treatment failures.
E. Olivares +5 more
semanticscholar +1 more source
Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis [PDF]
, 2018 In a retrospective analysis of 215 patients with carbapenem-resistant Pseudomonas aeruginosa sepsis, we observed a significantly higher risk of mortality associated with respiratory tract infection (risk ratio [RR], 1.20; 95 ...
Britt, Nicholas S +6 more
core +2 more sources
Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]
, 2013 Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown +27 more
core +2 more sources
Frontiers in Immunology, 2020 Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa, a major cause of chronic lung infections in cystic fibrosis (CF) and other settings.
Patrick R. Secor +16 more
semanticscholar +1 more source