Breaking the culture habit: Complementing culture-based veterinary diagnostics with metagenomic data -A case study of feline and canine skin infections. [PDF]
Ottesen A +8 more
europepmc +1 more source
Ear Piercing Complications: Comparing Cartilage and Soft Tissue Piercings in a Large Survey Cohort
Cartilage ear piercings were associated with significantly higher complication rates than lobule piercings and remained an independent predictor of complications after multivariate analysis. Cartilage site also independently predicted piercing removal, with higher removal rates observed compared to lobule piercings.
John P. Ziegler +6 more
wiley +1 more source
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran +7 more
wiley +1 more source
ABSTRACT Background Staphylococcus aureus (S. aureus) is a major cause of skin, wound, and device‐related infections. Blue light (405–470 nm), shows promise for treating this organism. However, the translatability, dosing parameters, safety, and effectiveness remain unclear, and no systematic review currently exists.
Alexander Idrogo‐Lam +3 more
wiley +1 more source
Evaluation of Antimicrobial Activity of Gallic Acid, Quercetin-3-D-Glucuronide, and Apigenin Against Gram-Negative Uropathogens: A Novel Approach to Urinary Tract Infection Therapy. [PDF]
Fydrych D +2 more
europepmc +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Emergence of bla<sub>NDM-1</sub> in Pseudomonas aeruginosa ST308 and ST773 from bloodstream infections in Egypt. [PDF]
AbdulHak A +4 more
europepmc +1 more source
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi +7 more
wiley +1 more source
Low concentrations of tetrasodium EDTA cause significant killing of biofilm-associated Pseudomonas aeruginosa in high-validity models of chronic wound and cystic fibrosis lung infections - but not in a model of endotracheal tube colonization. [PDF]
Orababa OQ +5 more
europepmc +1 more source
Debneyol decoded: A metabolic organizer powers broad‐spectrum plant defense
Abstract A new Cell study by Wang et al. resolves the long‐elusive biosynthesis and regulation of debneyol, a fungicidal sesquiterpenoid phytoalexin in Solanaceae. The authors define the complete three‐step route from farnesyl pyrophosphate to debneyol and identify the small protein MCD1 as a metabolic organizer that assembles a multienzyme complex to ...
Shaojie Han
wiley +1 more source

