Results 31 to 40 of about 9,193 (159)

Global asymptotic stability in a pseudorabies virus model with age structure

Infectious Disease Modelling, 2023
Pseudorabies is a highly contagious disease caused by pseudorabies virus (PRV) or suid herpesvirus 1 (SuHV1), causing significant economic losses to the swine industry in countries where the disease exists.
Yining Chen, Yuhua Long, Jianshe Yu
doaj   +1 more source

Human Endophthalmitis Caused By Pseudorabies Virus Infection, China, 2017

Emerging Infectious Diseases, 2018
We report human endophthalmitis caused by pseudorabies virus infection after exposure to sewage on a hog farm in China. High-throughput sequencing and real-time PCR of vitreous humor showed pseudorabies virus sequences. This case showed that pseudorabies
Jing-Wen Ai, Shan-Shan Weng, Qi Cheng, Peng Cui, Yong-Jun Li, Hong-Long Wu, Yi-Min Zhu, Bin Xu, Wen-Hong Zhang   +8 more
doaj   +1 more source

Pseudorabies gD protein protects mice and piglets against lethal doses of pseudorabies virus

Frontiers in Microbiology, 2023
IntroductionPseudorabies (PR) is a highly contagious viral disease caused by the pseudorabies virus (PRV), which can cause disease in a wide range of domestic and wild animals. Studies have shown that new mutant strains have emerged in pig farms in many regions and that commercial inactivated and live attenuated vaccines are becoming less effective at ...
Mengpo Zhao, Mengpo Zhao, Jing Chen, Shengjun Luo, Renhe Yan, Pian Zhang, Zhaowen Ren, Zhaowen Ren, Xiaofan Chen, Xiaofan Chen, Gang Wang, Hua Xiang, Rujian Cai, Yuan Huang, Na Li, Na Li, Hongwei Li, Zi-Guo Yuan, Xiaohu Wang   +18 more
openaire   +3 more sources

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

Biotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal, Asingsa W. Arachchige, Annabelle J. Zahn, S. Ranil Wickramasinghe, Xianghong Qian, Andrew L. Zydney   +5 more
wiley   +1 more source

Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

Frontiers in Veterinary Science, 2022
In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011.
Shijun Yan, Baicheng Huang, Xiaofei Bai, Ying Zhou, Linghua Guo, Tongyan Wang, Yihong Shan, Yuzhou Wang, Feifei Tan, Kegong Tian   +9 more
doaj   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, EarlyView.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing

BMC Neurology, 2023
Background Pseudorabies virus (PRV) was thought to only infect animals. Recent studies have shown that it can also infect human. Case presentation We report a case of pseudorabies virus encephalitis and endophthalmitis, diagnosed 89 days after onset ...
Yi Zhang, Lei Fang, Yi Zhou, Yongqing Zhang, Bing Liang, Chuanzhu Yan, Ling Li   +6 more
doaj   +1 more source

CULTIVATION OF PSEUDORABIES VIRUS [PDF]

Journal of Experimental Medicine, 1933
Pseudorabies virus has been cultivated in series in rabbit testicle, guinea pig testicle, and chick embryo media, and its growth requirements have been studied. Intranuclear inclusions, similar to those produced by pseudorabies virus in vivo, have been found in rabbit testicle cultures.
openaire   +2 more sources