Results 31 to 40 of about 9,326 (133)
Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1967-1975, July 2026.ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann +3 more
wiley +1 more source
Frontiers in Veterinary Science, 2022 In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011.
Shijun Yan +9 more
doaj +1 more source
MedComm, Volume 7, Issue 7, July 2026.Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
wiley +1 more source
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Advanced Science, Volume 13, Issue 34, 19 June 2026.Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Pathogenicity characteristics of different subgenotype pseudorabies virus in newborn piglets
Frontiers in Veterinary SciencePseudorabies virus is a major pathogen in the pig industry, causing substantial economic losses. The emergence of pseudorabies virus variant strains in China has led to extensive spread, raising concerns about their potential impact.
Lei Xu +9 more
doaj +1 more source
Advanced Science, Volume 13, Issue 24, 27 April 2026.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Vaccine resistant pseudorabies virus causes mink infection in China
BMC Veterinary Research, 2018 Background Pseudorabies, a highly contagious infectious disease of swine is caused by pseudorabies virus (PRV). PRV can cause fatal infection in other animal species. Results We report a deadly outbreak of pseudorabies that killed 87.2% (3522/4028) minks
Gui-sheng Wang +5 more
doaj +1 more source
BMC Neurology, 2023 Background Pseudorabies virus (PRV) was thought to only infect animals. Recent studies have shown that it can also infect human. Case presentation We report a case of pseudorabies virus encephalitis and endophthalmitis, diagnosed 89 days after onset ...
Yi Zhang +6 more
doaj +1 more source
Pathogens, 2021 Suid alphaherpesvirus 1 (SuHV-1), better known as Pseudorabies virus (PrV), an alphaherpesvirus of swine, is the causative agent of Aujeszky’s Disease [...]
Barbara G. Klupp
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.This study establishes a whole‐brain monosynaptic input map to cholinergic neurons in the lower thoracic intermediolateral column (IML) using a cell‐type‐specific retrograde rabies tracing system in ChAT‐Cre mice. Our results reveal a widespread supraspinal network originating from five major brain divisions, including the telencephalon, diencephalon ...
Yuan‐jun Yang +9 more
wiley +1 more source