Results 81 to 90 of about 8,705 (254)

Periumbilical perforating pseudoxanthoma elasticum: a rare case report

Dermatology Practical & Conceptual, 2018
Periumbilical perforating pseudoxanthoma elasticum (PPPXE) usually presents with well-defined periumbilical yellowish atrophic plaques with keratotic papules at the periphery.
Abhijeet K. Jha, MD Zeeshan, Binod K. Sinha, Anupama Singh, Pallavi Agrawal   +4 more
doaj  

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy. [PDF]

, 2017
Generalized arterial calcification of infancy (GACI) is an autosomal recessive disorder caused by mutations in the ENPP1 gene. It is characterized by mineralization of the arterial blood vessels, often diagnosed prenatally, and associated with death in ...
Kingman, Joshua, Li, Qiaoli, Uitto, Jouni   +2 more
core   +1 more source

Cardiac fibrosis in aging mice [PDF]

, 2016
Dystrophic cardiac calcinosis (DCC), also called epicardial and myocardial fibrosis and mineralization, has been detected in mice of a number of laboratory inbred strains, most commonly C3H/HeJ and DBA/2J. In previous mouse breeding studies between these
A Berndt, A Berndt, A Berndt, A Berndt, A Berndt, Annerose Berndt, AS Leme, Beth A. Sundberg, BT Ivandic, BT Ivandic, C Berthonneche, CD Rau, CH Firth, Clinton L. Cario, E Birkenmeier, G Jurisic, GJ Eaton, H Meng, HI Hamouda, HM Kang, IA Adzhubei, IJ Bristol, IN Mungrue, J Beckwith, J Uitto, JF Klement, JF Van Vleet, John P. Sundberg, Jouni Uitto, JP Sundberg, JP Sundberg, JP Sundberg, K Flurky, KA Silva, Kathleen A. Silva, M Atiq, M Ignat, M Koch, M Mahler, M Mahler, MA Farmer, Matthew A. Richardson, MC Hu, N Neu, P Vogel, Paul N. Schofield, PN Schofield, PN Schofield, Q Li, Q Li, Q Li, Q Li, Q Li, Q Li, Qiaoli Li, SJ Brown, SN Chen, SR Brunnert, T DiTommaso, TA Hough, TG Gorgels, TH Chase, Thomas H. Chase, U Kornak, U Mohr, Victoria E. Kennedy, VS Peche, Y Kim, Y Le Corre, Z Aherrahrou   +69 more
core   +2 more sources

Molecular Genetics and Modifier Genes in Pseudoxanthoma Elasticum, a Heritable Multisystem Ectopic Mineralization Disorder.

Journal of Investigative Dermatology, 2020
In the past two decades, there has been great progress in identifying the molecular basis and pathomechanistic details in pseudoxanthoma elasticum (PXE), a heritable multisystem ectopic mineralization disorder.
Hongbin Luo, M. Faghankhani, Yi Cao, J. Uitto, Qiaoli Li   +4 more
semanticscholar   +1 more source

Linear Focal Elastosis: A Peculiar Dermatosis

Clinical Case Reports, Volume 13, Issue 9, September 2025.
LFE confirmed by orcein stain showing fragmented elastic fibers within the reticular dermis. ABSTRACT Linear focal elastosis (LFE), also known as elastotic striae, is a rare cutaneous condition characterized by abnormal or increased deposition of elastic fibers in the dermis.
Adnan Ahmad, Fatmah Al‐Sughayer, Humoud Al‐Sabah, Atlal Al‐Lafi   +3 more
wiley   +1 more source

Pseudoxanthoma Elasticum as a Paradigm of Heritable Ectopic Mineralization Disorders: Pathomechanisms and Treatment Development.

American Journal of Pathology, 2019
Ectopic mineralization is a global problem and leading cause of morbidity and mortality. The pathomechanisms of ectopic mineralization are poorly understood. Recent studies on heritable ectopic mineralization disorders with defined gene defects have been
Qiaoli Li, K. van de Wetering, J. Uitto
semanticscholar   +1 more source

Relationship Between Mitochondrial Structure and Bioenergetics in Pseudoxanthoma elasticum Dermal Fibroblasts

Frontiers in Cell and Developmental Biology, 2020
Pseudoxanthoma elasticum (PXE) is a genetic disease considered as a paradigm of ectopic mineralization disorders, being characterized by multisystem clinical manifestations due to progressive calcification of skin, eyes, and the cardiovascular system ...
F. Lofaro, F. Boraldi, M. García-Fernández, Lara Estrella, P. Valdivielso, D. Quaglino   +5 more
semanticscholar   +1 more source

A case series of pseudoxanthoma elasticum-like disorders

Indian Journal of Dermatology, 2019
Pseudoxanthoma elasticum (PXE)-like papillary dermal elastolysis and focal dermal elastosis are acquired noninflammatory elastic tissue disorders. The skin lesions clinically resemble PXE without systemic involvement.
Sarah Bandar Aljoudi, Mohammed Haithm Abduljabbar, Jehad Osama Hariri   +2 more
doaj   +1 more source

Linear Focal Elastosis: What We Know From Epidemiological Studies

Australasian Journal of Dermatology, Volume 66, Issue 6, Page 364-368, September 2025.
ABSTRACT Linear focal elastosis (LFE), characterised by horizontal streaks on the lower back, is a dermatological condition with unclear etiopathogenesis and limited epidemiological data. This study synthesises case reports to elucidate demographic patterns, clinical manifestations, and potential associations. A literature search across PubMed, Embase,
Tim Aung, Rowland Noakes, Kais Kasem, Dedee F. Murrell   +3 more
wiley   +1 more source

Assessment of Inflammation and Calcification in Pseudoxanthoma Elasticum Arteries and Skin with 18F-FluroDeoxyGlucose and 18F-Sodium Fluoride Positron Emission Tomography/Computed Tomography Imaging: The GOCAPXE Trial

Journal of Clinical Medicine, 2020
Background: Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease characterized by elastic fiber fragmentation and ectopic calcification.
L. Omarjee, P. Mention, A. Janin, G. Kauffenstein, E. Le Pabic, O. Meilhac, Simon Blanchard, N. Navasiolava, G. Leftheriotis, O. Couturier, P. Jeannin, F. Lacoeuille, Ludovic Martin   +12 more
semanticscholar   +1 more source