Results 61 to 70 of about 6,809 (242)
Rare Co-occurrence of Beta-Thalassemia and Pseudoxanthoma elasticum: Novel Biomolecular Findings
Frontiers in Medicine, 2020 A number of beta-thalassemia patients, independently from the type of beta-thalassemia (β0 or β+) and blood transfusion requirements, may develop, after puberty, dermal, cardiovascular, and ocular complications associated with an ectopic mineralization ...
F. Boraldi +4 more
semanticscholar +1 more source
Angioid streaks. A case report
Medisur, 2011 Angioid streaks are breaks in Bruch's membrane displayed at the bottom of the eye as orange or gray bands around the optic disc, and from that point on they extend radially.
Aimé Broche Hernández +2 more
doaj +2 more sources
Pseudoxanthoma elasticum-like papillary dermal elastolysis
Definitions, 2020 Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) is a clinical-pathologic entity characterized by skin lesions similar to those of PXE itself in addition to the absence or marked loss of elastic fibers in the papillary dermis.
njihovo gostoto, Gostota Las
semanticscholar +1 more source
FEBS Open Bio, Volume 16, Issue 3, Page 474-486, March 2026.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Pseudoxanthoma elasticum and nephrocalcinosis [PDF]
Kidney International, 2016 Figure 2 | Fundus photograph. Characteristic peau d’orange pigmentary pattern in the periphery of the retina (triangle) and copious angioid streaks originating from the peripapillary region (arrows). A 36-year-old woman was referred to our clinic for nephrocalcinosis.
Seeger, Harald, Mohebbi, Nilufar
openaire +4 more sources
, 2022 The poster presentation will be covering the normal and abnormal histology of the disease, pseudoxanthoma elasticum. This disease is a rare disease that results from fragmenting of elastic fibers within connective tissue. Physical characteristics of this
Joe, Yuna
core
Frontiers in Cell and Developmental Biology, 2020 Pseudoxanthoma elasticum (PXE) is a genetic disease considered as a paradigm of ectopic mineralization disorders, being characterized by multisystem clinical manifestations due to progressive calcification of skin, eyes, and the cardiovascular system ...
F. Lofaro +5 more
semanticscholar +1 more source
Gram‐Scale Synthesis of an Arylsulfonamide‐Type Alkaline Phosphatase Inhibitor
ChemMedChem, Volume 21, Issue 4, 25 February 2026.A larger amount of a tissue‐nonspecific alkaline phosphatase inhibitor, 5‐((5‐chloro‐2‐methoxyphenyl)sulfonamido)nicotinamide, was synthesized in five steps using a parallel method without the need for chromatography or crystallization. Because a single batch was used for in vivo studies in a large population of mice, the pharmacological results were ...
Zsolt Rapi +2 more
wiley +1 more source
A New Zebrafish Model for Pseudoxanthoma Elasticum
Frontiers in Cell and Developmental Biology, 2021 Calcification of various tissues is a significant health issue associated with aging, cancer and autoimmune diseases. There are both environmental and genetic factors behind this phenomenon and understanding them is essential for the development of ...
Dávid Czimer +12 more
doaj +1 more source
Journal of Clinical Medicine, 2020 Background: Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease characterized by elastic fiber fragmentation and ectopic calcification.
L. Omarjee +12 more
semanticscholar +1 more source