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Abstract Psilocybin, a naturally occurring psychoactive compound found in more than 200 mushroom species, has an enduring history of use in sacred rituals of Indigenous healers worldwide. With selective serotonin receptor binding, activation of the serotonergic neurological system enables psilocybin to potentiate neuroplasticity ...
Jessi Humphreys +8 more
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Abstract Psilocybin, a naturally occurring psychoactive compound found in more than 200 mushroom species, has an enduring history of use in sacred rituals of Indigenous healers worldwide. With selective serotonin receptor binding, activation of the serotonergic neurological system enables psilocybin to potentiate neuroplasticity ...
Jessi Humphreys +8 more
+9 more sources
Reactions Weekly, 2023
Abstract Psilocybin is a psychoactive drug found in a variety of mushroom species around the world. It induces an altered state of consciousness that has been used in ceremonial settings since antiquity. It is now known beyond doubt that the psychoactive effect of psilocybin (more particularly, its active metabolite psilocin) is due to a
James J. Rucker, David Erritzoe
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Abstract Psilocybin is a psychoactive drug found in a variety of mushroom species around the world. It induces an altered state of consciousness that has been used in ceremonial settings since antiquity. It is now known beyond doubt that the psychoactive effect of psilocybin (more particularly, its active metabolite psilocin) is due to a
James J. Rucker, David Erritzoe
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The pharmacology of psilocybin
Addiction Biology, 2002AbstractPsilocybin (4‐phosphoryloxy‐N,N‐dimethyltryptamine) is the major psychoactive alkaloid of some species of mushrooms distributed worldwide.These mushrooms represent a growing problem regarding hallucinogenic drug abuse. Despite its experimental medical use in the 1960s, only very few pharmacological data about psilocybin were known until ...
Torsten, Passie +3 more
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Enzymatic Synthesis of Psilocybin
Angewandte Chemie - International Edition, 2017Abstract Psilocybin is the psychotropic tryptamine‐derived natural product of Psilocybe carpophores, the so‐called “magic mushrooms”. Although its structure has been known for 60 years, the enzymatic basis of its biosynthesis has remained obscure.
Dirk Hoffmeister, Janis Fricke
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The evolution and ecology of psilocybin in nature
Fungal Genetics and Biology, 2023Fungi produce diverse metabolites that can have antimicrobial, antifungal, antifeedant, or psychoactive properties. Among these metabolites are the tryptamine-derived compounds psilocybin, its precursors, and natural derivatives (collectively referred to as psiloids), which have played significant roles in human society and culture. The high allocation
Matthew, Meyer, Jason, Slot
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Availability of Websites Offering to Sell Psilocybin Spores and Psilocybin
Journal of Psychoactive Drugs, 2009This study assesses the availability of websites offering to sell psilocybin spores and psilocybin, a powerful hallucinogen contained in Psilocybe mushrooms. Over a 25-month period beginning in March 2003, eight searches were conducted in Google using the term "psilocybin spores." In each search the first 100 nonsponsored links obtained were scored by ...
Jason P, Lott +2 more
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