Results 1 to 10 of about 17,740 (123)

Actinium-225-PSMA versus lutetium-177-PSMA radioligand therapy for metastatic castration-resistant prostate cancer: results of an observational study [PDF]

open access: yesFrontiers in Oncology
BackgroundProstate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) with Lutetium-177 (177Lu) and Actinium-225 (225Ac) is increasingly used in metastatic castration-resistant prostate cancer (mCRPC), but head-to-head prospective data ...
Tatiana Yu Kochetova   +7 more
doaj   +2 more sources

Radiolabeled PSMA Inhibitors [PDF]

open access: yesCancers, 2021
PSMA has shown to be a promising target for diagnosis and therapy (theranostics) of prostate cancer. We have reviewed developments in the field of radio- and fluorescence-guided surgery and targeted photodynamic therapy as well as multitargeting PSMA inhibitors also addressing albumin, GRPr and integrin αvβ3.
Oliver C. Neels   +3 more
openaire   +4 more sources

Enzalutamide Enhances PSMA Expression of PSMA-Low Prostate Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) prolongs overall survival in men with metastatic castration-resistant prostate cancer (mCRPC). However, men with low PSMA expression are excluded from RLT. We explored the effect of androgen receptor blockade with enzalutamide on PSMA expression.
Magdalena Staniszewska   +11 more
openaire   +5 more sources

Therapeutic Outcomes of 177Lu-PSMA Targeted Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer: A Single-Center Study [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2023
Objective(s): This study aimed to evaluate the therapeutic outcomes of 177Lutetium (177Lu)-PSMA-617 in metastatic castrate-resistant prostate cancer (mCRPC) patients, based on post-treatment imaging findings.
Seyed Ali Mirshahvalad   +2 more
doaj   +1 more source

MODERN OPPORTUNITIES OF PET/CT IN THE DIAGNOSIS OF PROSTATE CANCER

open access: yesСибирский онкологический журнал, 2021
The purpose is to present a modern data on the possibilities of positron emission computed tomography combined with computed tomography (PET/CT) in the diagnosis, staging and monitoring of prostate cancer (PC).Material and Methods.
V. V. Vyazmin   +4 more
doaj   +1 more source

Study of Immunohistochemical Marker Psma and Ki 67 Expression and Its Relation with Grading in Prostate Carcinoma

open access: yesAnnals of Urologic Oncology, 2022
Background Prostate cancer (PCa) is the second most frequent malignancy (after lung cancer) in men worldwide .In prostate cancer, immunohistochemistry (IHC) has an important role in the diagnostic confirmation.
Amit V Varma   +5 more
doaj   +1 more source

Detection of circulating prostate cancer cells via prostate specific membrane antigen by chronoimpedimetric aptasensor

open access: yesTürk Biyokimya Dergisi, 2021
Sensitive and accurate techniques for early detection of prostate cancer, which has a good chance for successful treatment if detected early, are of utmost value. Our aim is to develop a sensitive chronoimpedimetric biosensor for detection of circulating
Uygun Zihni Onur, Girgin Sağin Ferhan
doaj   +1 more source

Preparation and Preliminary Imaging of Novel Albumin-Binding PSMA Ligand [177Lu]Lu-DOTA-CPN-PSMA

open access: yesHe huaxue yu fangshe huaxue, 2023
A novel PSMA targeting molecule [177Lu]Lu-DOTA-CPN-PSMA with high uptake and long retention in prostate cancer was developed, in which DOTA was used as the bifunctional chelator, glutamic acid-urea-lysine(Glu-Urea-Lys) was used as the targeting group ...
LUO Tian-wei   +7 more
doaj   +1 more source

(Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer

open access: yesPharmaceuticals, 2020
The role of nuclear medicine in the management of oncological patients has expanded during last two decades. The number of radiopharmaceuticals contributing to the realization of theranostics/radiotheranostics in the context of personalized medicine is ...
Irina Velikyan
doaj   +1 more source

Diagnostic Value of 18F-labeled PSMA PET/CT for Regional Lymph Node Metastasis in Prostate Cancer: A Meta-analysis

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To evaluate the diagnostic value of 18F-labeled PSMA PET/CT for regional lymph node metastasis in prostate cancer. Methods We searched PubMed, Embase, Cochrane Library, Web of Science, CNKI, VIP and Wanfang database from January 1, 2000 to May ...
ZENG Chunyuan, CHENG Yong, XU Hao
doaj   +1 more source

Home - About - Disclaimer - Privacy