Results 11 to 20 of about 17,785 (168)

Therapeutic potential of targeting mirnas to prostate cancer tumors: using psma as an active target

open access: yesMolecular & Cellular Oncology, 2022
Prostate cancer (PC) is a commonly diagnosed malignancy in men and is associated with high mortality rates. Current treatments for PC include surgery, chemotherapy, and radiation therapy. However, recent advances in targeted delivery systems have yielded
Amir Yarahmadi   +3 more
doaj   +1 more source

Radiotheranostics is here to help [PDF]

open access: yesDigital Diagnostics, 2021
The COVID-19 pandemic did not diminish interest in radiotheranostics. However, the demand for visualization of pathological processes using cross-sectional and hybrid imaging (CT, MRI, SPECT, and PET) is increased.
Rumyantsev O. Rumyantsev
doaj   +1 more source

PSMA Targeted Molecular Imaging and Radioligand Therapy for Prostate Cancer: Optimal Patient and Treatment Issues

open access: yesCurrent Oncology, 2023
Theranostics (therapy + diagnosis) targeting prostate-specific membrane antigen (PSMA) is an emerging therapeutic modality that could alter treatment strategies for prostate cancer.
Seiji Hoshi   +11 more
doaj   +1 more source

[68Ga]Ga-PSMA PET/MRI, histological PSMA expression and preliminary experience with [177Lu]Lu-PSMA therapy in relapsing high-grade glioma

open access: yesFrontiers in Oncology, 2022
PurposeHigh-grade gliomas (HGG) are still associated with a dismal prognosis. Prostate specific membrane antigen (PSMA) is discussed as a theranostic target for PSMA-directed radioligand therapy ([177Lu]Lu-PSMA RLT). Here, we report on the correlation of
Peter Truckenmueller   +13 more
doaj   +1 more source

Precision low-dose brachytherapy of prostate cancer under PSMA-receptor molecular visualization [PDF]

open access: yesDigital Diagnostics, 2023
Brachytherapy with implantation of micro sources based on isotope 125I is a preferred treatment for localized prostate cancer without signs of germination of the gland capsule and in the absence of signs of metastases (stage cT1-T23aN0M0).
Pavel V. Sviridov   +7 more
doaj   +1 more source

Targeted Radiotherapeutics from 'Bench-to-Bedside'

open access: yesCHIMIA, 2020
he concept of targeted radionuclide therapy (TRT) is the accurate and efficient delivery of radiation to disseminated cancer lesions while minimizing damage to healthy tissue and organs.
Cristina Müller   +4 more
doaj   +1 more source

An Albumin-Binding PSMA Ligand with Higher Tumor Accumulation for PET Imaging of Prostate Cancer

open access: yesPharmaceuticals, 2022
Prostate-specific membrane antigen (PSMA) is an ideal target for the diagnosis and treatment of prostate cancer. Due to the short half-life in blood, small molecules/peptides are rapidly cleared by the circulatory system. Prolonging the half-life of PSMA
Ya’nan Ren   +6 more
doaj   +1 more source

Imaging of Tumor-Associated Vascular Prostate-Specific Membrane Antigen in Woodchuck Model of Hepatocellular Carcinoma

open access: yesGastro Hep Advances, 2022
Background and Aims: Radiolabeled short peptide ligands targeting prostate-specific membrane antigen (PSMA) were developed initially for imaging and treatment of prostate cancers.
Olga Sergeeva   +14 more
doaj   +1 more source

Preclinical comparative study of [18F]AlF-PSMA-11 and [18F]PSMA-1007 in varying PSMA expressing tumors

open access: yesScientific Reports, 2022
A wide variety of 18F-labeled PSMA-targeting PET radiotracers have been developed, including [18F]AlF-PSMA-11. As there is only limited data on the comparison with other 18F-labeled PSMA PET tracers, a comparative preclinical study between [18F]AlF-PSMA ...
Sarah Piron   +8 more
doaj   +1 more source

68Ga–Prostate-Specific Membrane Antigen: A Potential Radiopharmaceutical in PET/CT To detect primary Cholangiocarcinoma [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2020
68Ga Prostate-specific membrane antigen (PSMA) is an increasingly popular radiopharmaceutical tracer in prostate cancer and is becoming increasingly researched in other cancers such as breast cancer, renal cell carcinoma, glioblastoma multiforme, among ...
Rita Chahinian   +5 more
doaj   +1 more source

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