Results 71 to 80 of about 21,032 (282)

The Dark Side of the Light: Phototherapy Adverse Effects [PDF]

open access: yes, 2016
Phototherapy is a valuable therapeutic tool in Dermatology, but there may be drawbacks. Acute and long-term adverse effects, of variable severity, include skin erythema, xerosis, pruritus, blistering, altered pigmentation, photoaging, and ...
Apetato, M, Valejo Coelho, M
core   +1 more source

HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh   +3 more
wiley   +1 more source

A study of comparison of PUVASOL and NBUVB in patients with vitiligo

open access: yesPigment International, 2018
Introduction: Vitiligo is an acquired, hypomelanotic disease, characterized by circumscribed depigmented macules. Phototherapy, which is the use of ultraviolet irradiation with or without exogenous photosensitizer is a well established treatment option ...
Vaaruni Ravishankar   +4 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins

open access: yesMolecules, 2014
A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated
Alla V. Lipeeva   +4 more
doaj   +1 more source

Brentuximab vedotin and radiotherapy for CD30‐positive cutaneous T‐cell lymphoma – a retrospective multicenter analysis

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives While brentuximab vedotin (BV) and radiotherapy (RTx) are established treatment options for CD30‐positive cutaneous T‐cell lymphoma (CTCL), data on their simultaneous or sequential use regarding efficacy and tolerability remain scarce.
Patrick Schummer   +10 more
wiley   +1 more source

An Efficient Synthetic Strategy for the Preparation of Nucleic Acid-Encoded Peptide and Protein Libraries for In Vitro Evolution Protocols

open access: yesMolecules, 2000
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis.
Peter A. Lohse   +2 more
doaj   +1 more source

Genome-wide profiling of human cap-independent translation-enhancing elements. [PDF]

open access: yes, 2013
We report an in vitro selection strategy to identify RNA sequences that mediate cap-independent initiation of translation. This method entails mRNA display of trillions of genomic fragments, selection for initiation of translation and high-throughput ...
Briones, Natalia   +10 more
core  

Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]

open access: yes, 2008
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P.   +4 more
core   +1 more source

Variation in forage quality and chemical composition among Italian accessions of Bituminaria bituminosa (L.) Stirt. [PDF]

open access: yes, 2007
Native Bituminaria bituminosa (L.) Stirt. accessions from central and southern Italy were evaluated for chemical composition to assess their nutritional value as forages.
Bertoli   +29 more
core   +1 more source

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