Results 71 to 80 of about 19,791 (256)
In vitro demonstration of herbal exacerbation of paracetamol-induced hepatotoxicity
Background: Paracetamol (acetaminophen) is one of the most accessible pharmaceutical analgesic and antipyretic agents. Similarly, traditional herbal medicines including Psoralea corylifolia, Astragalus propinquus and Atractylodes macrocephala have been ...
Susan M. Britza+3 more
doaj
Lime-induced phytophotodermatitis [PDF]
This case describes a scenario of lime-induced phytophotodermatitis. Phytophotodermatitis is a dermatitis caused after the skin is exposed to photosensitizing compounds in plants and then exposed to sunlight.
Andrew Hankinson+2 more
doaj +1 more source
Profound Thrombocytopenia and Dyspnea 11 Days After Cardiac Surgery
American Journal of Hematology, EarlyView.
Sebastian Vuong+3 more
wiley +1 more source
In dieser Studie wird eine Methode zur präzisen Kontrolle von Retinsäure‐Induzierbaren‐Gens‐I (RIG‐I) vorgestellt, einem Rezeptor des angeborenen Immunsystems, der, wenn er aktiviert wird, antitumorale Immunreaktionen und Zelltod von Krebszellen auslöst.
Sandra Anika Lewash+11 more
wiley +1 more source
This study presents a method for precise control of RIG‐I (retinoic acid inducible gene I), an innate immune receptor of RNA that, when activated, induces anti‐tumor immune responses and cancer cell death. By incorporating photocage modifications into RNA ligands, we enable a spatially and temporally regulated immune response and offer a targeted ...
Sandra Anika Lewash+11 more
wiley +1 more source
Toward new gold(III) anticancer agents. Herein, we report on an indazole‐based gold(III) carboxamide pincer complex exhibiting significant cytotoxicity, likely mediated through dual interactions with DNA. Mechanistic investigations suggest that the complex binds to the DNA and forms specific interactions with nucleotide bases.
Rufaro Razuwika+4 more
wiley +1 more source
Efficacy of Narrowband UVB vs. PUVA in Patients with Early-Stage Mycosis Fungoides [PDF]
INTRODUCTION: Mycosis fungoides (MF) is a non-Hodgkin's T-cell lymphoma of the skin that often begins as limited patches and plaques with slow progression to systemic involvement.
Apetato, M, Ponte, P, Serrão, V
core +1 more source
Alopecia Areata: Pathogenesis, Diagnosis, and Therapies
This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma+7 more
wiley +1 more source
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis.
Peter A. Lohse+2 more
doaj +1 more source
Contributions of in situ hybridization of sRNA to the study on spatio-temporal gene expression in Hevea brasiliensis [PDF]
Since the dawn of the genomics era, much research has focused on functional studies of genes of interest. In situ hybridization is a method that can be used to precisely localize the expression of a gene in tissues and cells.
Alemanno, Laurence+6 more
core