Results 81 to 90 of about 18,017 (225)
Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins
A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated
Alla V. Lipeeva +4 more
doaj +1 more source
Medical Phototherapy Malpractice and Legal Precedents in North America (1983–2025)
International Journal of Dermatology, EarlyView.
Ghassan Barnawi +6 more
wiley +1 more source
Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US
ABSTRACT Vitiligo is a chronic autoimmune depigmenting disease characterized by loss of pigment in the skin, hair, or both. As treatment options evolve, particularly with the emergence of oral Janus kinase inhibitors and dual Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, it is essential to assess ...
Kennedy Cook +11 more
wiley +1 more source
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis.
Peter A. Lohse +2 more
doaj +1 more source
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs +6 more
wiley +1 more source
KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages [PDF]
Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype.
Catalano, M +11 more
core +2 more sources
Mechanistic Insights Into the Photosensitizing Properties of the Topical Retinoid Tazarotene
Light‐activated retinoids: Tazarotene and its active metabolite tazarotenic acid form long‐lived triplet excited states upon UVA irradiation, generating singlet oxygen and promoting photochemical reactions. These processes correlate with reduced fibroblast viability under light exposure, revealing potential phototoxicity and implications for combined ...
Juan A. Soler‐Orenes +5 more
wiley +1 more source
Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
Yong-Tai Zhang, Li-Na Shen, Ji-Hui Zhao, Nian-Ping FengDepartment of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaAbstract: This study aimed to improve skin permeation and ...
Zhang YT, Shen LN, Zhao JH, Feng NP
doaj
Furanocoumarins are the major phytoalexins of Ficus carica and are effective natural drug candidates for treatment of several types of cancer and skin disease.
Samia Rouaiguia-Bouakkaz +5 more
doaj +1 more source
Variation in forage quality and chemical composition among Italian accessions of Bituminaria bituminosa (L.) Stirt. [PDF]
Native Bituminaria bituminosa (L.) Stirt. accessions from central and southern Italy were evaluated for chemical composition to assess their nutritional value as forages.
Bertoli +29 more
core +1 more source

