Results 81 to 90 of about 18,017 (225)

Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins

open access: yesMolecules, 2014
A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated
Alla V. Lipeeva   +4 more
doaj   +1 more source

Medical Phototherapy Malpractice and Legal Precedents in North America (1983–2025)

open access: yes
International Journal of Dermatology, EarlyView.
Ghassan Barnawi   +6 more
wiley   +1 more source

Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US

open access: yesThe Journal of Dermatology, Volume 53, Issue 5, Page 758-773, May 2026.
ABSTRACT Vitiligo is a chronic autoimmune depigmenting disease characterized by loss of pigment in the skin, hair, or both. As treatment options evolve, particularly with the emergence of oral Janus kinase inhibitors and dual Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, it is essential to assess ...
Kennedy Cook   +11 more
wiley   +1 more source

An Efficient Synthetic Strategy for the Preparation of Nucleic Acid-Encoded Peptide and Protein Libraries for In Vitro Evolution Protocols

open access: yesMolecules, 2000
We describe an improved synthetic strategy for the preparation of nucleic acid encoded peptide and protein libraries. A solid-phase format was used to prepare and purify a novel type of mRNA-template for in vitro mRNA-protein fusion synthesis.
Peter A. Lohse   +2 more
doaj   +1 more source

Untargeted Metabolomic and Lipidomic Profiles of Gingival Crevicular Fluid in the Context of Periodontitis

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 5, Page 774-783, May 2026.
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs   +6 more
wiley   +1 more source

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages [PDF]

open access: yes, 2016
Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype.
Catalano, M   +11 more
core   +2 more sources

Mechanistic Insights Into the Photosensitizing Properties of the Topical Retinoid Tazarotene

open access: yesChemMedChem, Volume 21, Issue 8, 28 April 2026.
Light‐activated retinoids: Tazarotene and its active metabolite tazarotenic acid form long‐lived triplet excited states upon UVA irradiation, generating singlet oxygen and promoting photochemical reactions. These processes correlate with reduced fibroblast viability under light exposure, revealing potential phototoxicity and implications for combined ...
Juan A. Soler‐Orenes   +5 more
wiley   +1 more source

Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis

open access: yesInternational Journal of Nanomedicine, 2014
Yong-Tai Zhang, Li-Na Shen, Ji-Hui Zhao, Nian-Ping FengDepartment of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaAbstract: This study aimed to improve skin permeation and ...
Zhang YT, Shen LN, Zhao JH, Feng NP
doaj  

Identification and Quantification of Furanocoumarins in Stem Bark and Wood of Eight Algerian Varieties of by RP-HPLC-DAD and RP-HPLC-DAD-MS

open access: yesNatural Product Communications, 2013
Furanocoumarins are the major phytoalexins of Ficus carica and are effective natural drug candidates for treatment of several types of cancer and skin disease.
Samia Rouaiguia-Bouakkaz   +5 more
doaj   +1 more source

Variation in forage quality and chemical composition among Italian accessions of Bituminaria bituminosa (L.) Stirt. [PDF]

open access: yes, 2007
Native Bituminaria bituminosa (L.) Stirt. accessions from central and southern Italy were evaluated for chemical composition to assess their nutritional value as forages.
Bertoli   +29 more
core   +1 more source

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