Results 101 to 110 of about 18,017 (225)

Anti-tumor effect and hepatotoxicity mechanisms of psoralen

Frontiers in Pharmacology
In recent years, natural products have gradually become an important source for new drug development due to their advantages of multi-components, multi-targets, and good safety profiles.
Dandan Meng, Yanling Dong, Qingxin Shang, Ziyuan Sun   +3 more
doaj   +1 more source

The effects of CYP2B6 inactivators on the metabolism of ciprofol.

PLoS ONE
Ciprofol is a novel short-acting intravenous anaesthetic developed in China that is mainly metabolized by cytochrome P450 2B6 (CYP2B6) and uridine diphosphate glucuronosyltransferase 1A9 (UGT1A9).
Ming Lu, Xiaorui Zhang, Wenli Li, Xiangchen Li, Shan Li, Xiaoyu Yin, Zhiqing Zhang   +6 more
doaj   +1 more source

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus [PDF]

, 1994
Endotoxin (lipopolysaccharide, LPS) is commonly found as a contaminant in plasmid DNA preparations. We demonstrate here that the quantities of LPS typically contaminating DNA preparations can generate a toxicity to primary cells (primary human skin ...
Baker, A., Buschle, M., Cotten, Matt, Saltik, Mediyha, Wagner, Ernst   +4 more
core  

Psoralen Suppresses Cisplatin-Mediated Resistance and Induces Apoptosis of Gastric Adenocarcinoma by Disruption of the miR196a-HOXB7-HER2 Axis

Cancer Management and Research, 2020
Lei Jin,1,2,* Xue-Mei Ma,1,2,* Ting-Ting Wang,1,2 Yao Yang,1,2 Nan Zhang,2,3 Na Zeng,2,4 Zhi-Gang Bai,1,2 Jie Yin,1,2 Jun Zhang,1,2 Guo-Qian Ding,1,2 Zhong-Tao Zhang1,2 1Department of General Surgery, Beijing Friendship Hospital, Capital Medical ...
Jin L, Ma XM, Wang TT, Yang Y, Zhang N, Zeng N, Bai ZG, Yin J, Zhang J, Ding GQ, Zhang ZT   +10 more
doaj  

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Psoralens. [PDF]

BMJ, 1969
openaire   +3 more sources

Synthesis of novel psoralen analogues and their anti-proliferative effect on human cancer cell lines [PDF]

, 2011
We describe the synthesis of 3H-benzofuro[3,2-f]chromen-3-ones. The anti-proliferative effect on human cancer cell lines (MDA-MB231 and HeLa) was evaluated.FCT and FEDER, for National NMR ...
Campos, Ana M. F. Oliveira, Francisco, Carla Santana, Rodrigues, L. R., Rodrigues, Lígia M.   +3 more
core  

Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate [PDF]

, 1994
Cook, Deborah R., Curiel, David T., Curiel, Tyler J., Glode, L. M., Maxwell, F., Maxwell, I. H., Purner, M. B., Stevens, J. O., Wagner, Ernst   +8 more
core   +1 more source

Possible role of psoralen-induced phototoxicity in the development of vitiligo

JAAD Case Reports, 2022
Genevieve Patrick, BS, Parastou Shahzeidi, BS, Alexzandra Mattia, BS, Christopher Downing, MD, Armand Cognetta, MD   +4 more
doaj   +1 more source

Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells

International Journal of Nanomedicine, 2019
Yueling Yuan,1,* Tiange Cai,2,* Richard Callaghan,3,* Qianwen Li,4 Yinghong Huang,4 Bingyue Wang,1 Qingqing Huang,1 Manling Du,1 Qianqian Ma,1 Peter Chiba,5 Yu Cai1,6 1College of Pharmacy, Jinan University, Guangzhou, Guangdong 510632, China; 2College ...
Yuan Y, Cai T, Callaghan R, Li Q, Huang Y, Wang B, Huang Q, Du M, Ma Q, Chiba P, Cai Y   +10 more
doaj