scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions
Journal of the European Academy of Dermatology and Venereology, EarlyView.CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu +13 more
wiley +1 more source
Chromatin structure and methylation of rat rRNA genes studied by formaldehyde fixation and psoralen cross-linking [PDF]
, 2017 By using formaldehyde cross-linking of histones to DNA and gel retardation assays we show that formaldehyde fixation, similar to previously established psoralen photocross-linking, discriminates between nucleosome-packed (inactive) and nucleosome-free ...
Koller, Theodor +3 more
core
Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies [PDF]
, 2006 Eight psoralens have been evaluated for their ability to inhibit the in vitro growth of three human turner cell lines representing different tumor types, MCF-7 (breast cancer), NCI-14460 (non-small cell lung cancer) and SF-268 (CNS cancer). The synthesis
Afonso, Carlos A. M. +9 more
core +1 more source
An Early Record of Photochemotherapy for Vitiligo by Rhazes (865–925 ce) in Liber Continens
JEADV Clinical Practice, EarlyView.
Alireza Tavakkoli
wiley +1 more source
Pediatric Papular Mycosis Fungoides Treated With Phototherapy: A Case Series
Pediatric Dermatology, EarlyView.ABSTRACT Papular mycosis fungoides (PMF) is a rare clinical variant with limited data on long‐term outcomes, particularly in children. Our study describes sociodemographic, clinical, therapeutic, and follow‐up data in 5 pediatric patients with PMF, all treated with phototherapy (PUVA, PUVAsol or narrowband UVB).
Mariana de la Vega +3 more
wiley +1 more source
Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
International Journal of Nanomedicine, 2014 Yong-Tai Zhang, Li-Na Shen, Ji-Hui Zhao, Nian-Ping FengDepartment of Pharmaceutical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaAbstract: This study aimed to improve skin permeation and ...
Zhang YT, Shen LN, Zhao JH, Feng NP
doaj
Cellular Physiology and Biochemistry, 2018 Background/Aims: Psoralen and bakuchiol are the main active compounds found in the traditional Chinese medicine Psoralea corylifolia L., and have been used to treat osteoporosis.
Lijuan Chai +8 more
doaj +1 more source
Biodegradable nanoparticles containing benzopsoralens : an attractive strategy for modifying vascular function in pathological skin disorders [PDF]
, 2011 Psoralens are often used to treat skin disorders such as psoriasis, vitiligo and others. The toxicity and fast degradation of these drugs can be diminished by encapsulation in drug delivery systems (DDS). Nanoparticles (NPs) containing the benzopsoralen (
Bendhack, Lusiane M. +6 more
core +1 more source
Vitiligo Arising at the Injection Site of Interferon‐α
JEADV Clinical Practice, EarlyView.
Yubin Peng, Tao Wang
wiley +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
Photochemistry and Photobiology, EarlyView.The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source