Results 51 to 60 of about 3,770 (221)

Assessment of Treatment Response in Patients With Scleromyxedema by the Double Modified Rodnan Skin Score

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley   +1 more source

Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study

open access: yesJEADV Clinical Practice, EarlyView.
This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio   +8 more
wiley   +1 more source

Clinical pearls in anesthesia for excision and reconstructive surgery for cauliflower carcinoma on psoriatic plaques

open access: yesThe Indian Anaesthetists' Forum, 2017
Meticulous preoperative evaluation and planning is essential in psoriasis patients presenting for surgery as the airway and axial skeleton may both be involved in addition to extensive integumentary involvement.
Shagun Bhatia Shah, Anita Kulkarni
doaj   +1 more source

Ask a pathologist [PDF]

open access: yes, 2017
This article answers the question: Our hospital blood bank has started using platelet additive solution (PAS) platelets and psoralen treated platelets.
Coberly, Emily
core   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens

open access: yesJournal of Nucleic Acids, 2010
Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We
Rajagopal Krishnan, Dennis H. Oh
doaj   +1 more source

Methoxsalen-induced macular toxicity

open access: yesIndian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +1 more source

A theoretical insight into the photophysics of psoralen [PDF]

open access: yes, 2006
Psoralen photophysics has been studied on quantum chemistry grounds using the multiconfigurational second-order perturbation method CASPT2. Absorption and emission spectra of the system have been rationalized by computing the energies and properties of ...
Bonnett R.   +9 more
core   +2 more sources

Epidemiology, Diagnosis and Management of Alopecia Areata: An Asia‐Pacific Modified Delphi Expert Panel Recommendations

open access: yesInternational Journal of Dermatology, EarlyView.
A panel of 18 dermatologists participated in a three‐round Delphi‐based consensus process to generate a standardized framework for the diagnosis and management of alopecia areata (AA) in Asia Pacific. Recommendations focus on practicality and clinical relevance within the regional context.
Rodney Sinclair   +17 more
wiley   +1 more source

Severe hepatotoxicity by Indian Ayurvedic herbal products: A structured causality assessment

open access: yesAnnals of Hepatology, 2009
The case of a 64 year old female patient is presented who has treated herself for 9 months with various Indian Ayurvedic herbal products for her vitiligo and experienced a causally related severe hepatotoxicity (ALT, 601 U/L; AST, 663 U/L; Bilirubin, 5.0
Rolf Teschke, Ruediger Bahre
doaj   +1 more source

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