The human DNA glycosylases NEIL1 and NEIL3 excise psoralen-induced DNA-DNA cross-links in a four-stranded DNA structure [PDF]
, 2017 Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked ...
A Katafuchi +44 more
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Dermatologica Sinica, 2015 The etiology of granuloma annulare (GA) remains unknown, although several eliciting factors have been proposed. We herein present the case of an 81-year-old man who developed generalized erythematous annular plaques 6 months after engraftment of a ...
Han-Chi Tseng, Chih-Hung Lee
doaj +1 more source
Using a Topical Formulation of Vitamin D for the Treatment of Vitiligo: A Systematic Review
Cells, 2023 Vitamin D is one significant prohormone substance in human organ systems. It is a steroidal hormone produced in the skin upon exposure to UVB rays.
Khadeejeh Al-Smadi +6 more
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DNA-psoralen: single-molecule experiments and first principles calculations
, 2010 The authors measure the persistence and contour lengths of DNA-psoralen complexes, as a function of psoralen concentration, for intercalated and crosslinked complexes. In both cases, the persistence length monotonically increases until a certain critical
Alexandre, S. S. +4 more
core +1 more source
Novel benzopsoralen analogues : synthesis, biological activity and molecular docking studies [PDF]
, 2014 New benzopsoralen analogues were synthesized and their inhibitory effect on the growth of tumourtumour cell lines (MDA MB231 and TCC-SUP) was evaluated.
Campos, Ana M. F. Oliveira +4 more
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Anais Brasileiros de Dermatologia, 2010 Duas adolescentes e uma menina com vitiligo clinicamente diagnosticado foram tratadas com 8-metoxipsoraleno a 0,2% em creme Lanette com subsequente exposição solar. Um ano após, apresentaram máculas acrômicas na área do vitiligo.
Nurimar Conceição Fernandes +1 more
doaj +1 more source
The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism [PDF]
, 2016 K
Hegedűs, Csaba +6 more
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Biodegradable nanoparticles containing benzopsoralens : an attractive strategy for modifying vascular function in pathological skin disorders [PDF]
, 2011 Psoralens are often used to treat skin disorders such as psoriasis, vitiligo and others. The toxicity and fast degradation of these drugs can be diminished by encapsulation in drug delivery systems (DDS). Nanoparticles (NPs) containing the benzopsoralen (
Bendhack, Lusiane M. +6 more
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Nail changes associated with pigmentary disorders
Pigment International, 2021 Salient nail unit changes serve as pointers toward systemic disease. On similar lines, salient nail changes are associated with pigmentary disorders, and can help toward diagnosis.
Chander Grover, Shikha Bansal
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High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. [PDF]
, 1992 The Boltzmann transport equation is commonly considered to be the best semi-classical description of carrier transport in semiconductors, providing precise information about the distribution of carriers with respect to time (one dimension), location ...
Birnstiel, Max L. +5 more
core +2 more sources